Application Notes

The rugged C18 column design provides large loading capacities and great reliability required for repeated use in manufacturing production lines.

This note discusses the characterization of conformational properties of hyperbranched macromolecules by combining SEC-MALS with differential viscometry.

This note discusses the characterization of conformational properties of hyperbranched macromolecules by combining SEC-MALS with differential viscometry.

How do biologics compare to small molecules? There's a lot to learn when you're new to bioanalysis. This infographic offers a fun way to get started.

This application compendium demonstrates the utility of a complete suite of ion-exchange columns for charge variant analysis to characterize biotherapeutic proteins.

Discover reliable, accurate analyses across biopharma, including the determination of CQAs, metabolomics, oligos, and more in this application compendium.

This application demonstrates excellent performance in method development for the analysis of raw materials for oligonucleotide synthesis using a biocompatible UHPLC.

This application note describes the drug-to-antibody determination of brentuximab vedotin using a ternary gradient with isopropanol as third channel organic modifier.

This application compendium demonstrates the power of specialty affinity chromatography columns for the isolation and quantitation of monoclonal antibodies.

Explore high-resolution peptide separations in this application compendium that use superficially porous and sub-2 µm reversed-phase columns at HPLC and UHPLC pressure.

Learn about a high-quality peptide separation, which is crucial for primary structure and PTM analysis of mAbs, using a biocompatible UHPLC in this application note.

This application compendium shows everything you need for N-glycan analysis—including easy sample prep kits, labeled and unlabeled glycan standards, enzymes, and columns.

To monitor FcR receptor binding, a recombinant FcγRIIIa-ligand has been commercialized into TSKgel FcR-IIIA high-performance affinity chromatography (AFC) columns that separate antibodies based on affinity differences to FcγRIIIa.

This technical article outlines the analysis of long-chain oligonucleotides utilizing a simple eluent containing acetonitrile with a relatively low level of salt and no ion-pair reagent.

With a multitude of health applications, garlic separations appear to be a necessary quest.

In order to evaluate and test the robustness of cannabinoid analysis using the miniLC, a method was chosen from the literature and compared to data from the miniLC system. Comparison of retention time of standards to published values indicates the miniLC provides an excellent alternative with comparable results to a more expensive, complicated liquid chromatography system

Spinach and other highly pigmented vegetables contain chlorophylls, carotenoids, xanthophylls, and anthocyanins. Chlorophylls have the greatest adverse effect on gas chromatography systems due to their non-volatile characteristics. This QuEChERS procedure uses ChloroFiltr to significantly reduce chlorophylls without sacrificing the recoveries of planar pesticides.

This study demonstrates how to increase sample throughput for glycan characterization workflows using the Agilent AssayMAP Bravo liquid handling platform.