Application Notes

Whether the application is wet, dry, or cryogenic, consistent and viable representation of sample preparation leads to more accurate and repeatable results for analysis.

This note summarises a procedure developed by the US Food and Drug Administration to measure 16 PFAS in food using a QuEChERS sample preparation approach and LC–MS/MS analysis.  

Purification of peptide-peptoid hybrids can be obtained by reversed phase chromatography with excellent recovery and resolution.

The ability to collect compounds is directly related to the ability to detect them. Many compounds possess weak or non-existent chromophores which causes UV detection to exhibit poor yields.

The development of comprehensive liquid chromatography–high resolution accurate mass workflows for confident identification and mapping of oligonucleotides.

PFAS are known to be persistent in the environment. Detecting low levels of PFAS in drinking water is made easier using an Activated Carbon Delay Column.

Sampling and analysis of a challenging range of trace-level volatile & semi-volatile vapours of per- & polyfluorinated alkyl substances (PFAS) in air using TD–GC–MS

The effect of various ion pairing reagents (amines and acidic counterions) on the LC–UV and LC–MS analysis of oligonucleotides (ONs) has been studied.

Use software to deconvolute LC–MS spectra from complex samples and identify unknown components.

Plasticizers added to water bottles to add stability to the bottles can be unknowingly extracted in drinks leading to possible endocrine interactions. 

The Agilent MassHunter Optimizer software for GC Triple Quad (GC/TQ) can help generate multiple reaction monitoring transitions for newly added compounds.

This application note provides an example of a novel food authenticity workflow that can be used for food classification and detection of food fraud.

This application note describes the analysis of volatile organic compounds (VOCs) analysis in soil and sediments using a headspace sampler and GC–MS system.

Thermal extraction desorption-gas chromatography–mass spectrometry method automation, increased sample throughput, for quantifying microplastics in environmental samples

Data creates alternate testing protocol for U.S. Environmental Protection Agency for GC–MS analysis of tetra- through octa-dioxins and furans equivalent to EPA Method 1613B

This study shows how centrifugal partition chromatography can produce a high-quality standard of [6]-gingerol without the use of silica-based chromatography methods.

This methodology demonstrates an efficient approach for identity and stability testing of lipids and lipid-based formulations like mRNA vaccines by HPTLC.