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Development and Validation of GC/TQ Methods for the Analysis of Hazardous Chemicals
The Agilent MassHunter Optimizer software for GC Triple Quad (GC/TQ) can help generate multiple reaction monitoring transitions for newly added compounds.
Workflow for Food Classification and Authenticity Using Yerba Mate and High-Resolution GC/Q-TOF v4
This application note provides an example of a novel food authenticity workflow that can be used for food classification and detection of food fraud.
Volatile Organic Compounds Analysis in Soils and Sediments Using the Agilent 8697 Headspace Sampler
This application note describes the analysis of volatile organic compounds (VOCs) analysis in soil and sediments using a headspace sampler and GC–MS system.
Accelerated Determination of Microplastics in Environmental Samples Using Thermal Extraction Desorption-Gas Chromatography/Mass Spectrometry (TED-GC/MS)
Thermal extraction desorption-gas chromatography–mass spectrometry method automation, increased sample throughput, for quantifying microplastics in environmental samples
An Alternative to EPA Method 1613B: Determination of 2,3,7,8-Substituted Tetra- through Octa-Chlorinated Dibenzo-p-Dioxins and Dibenzofurans (CDDs/CDFs) Using Agilent Triple Quadrupole GC–MS
Data creates alternate testing protocol for U.S. Environmental Protection Agency for GC–MS analysis of tetra- through octa-dioxins and furans equivalent to EPA Method 1613B
Purification of Gingerol by CPC
This study shows how centrifugal partition chromatography can produce a high-quality standard of [6]-gingerol without the use of silica-based chromatography methods.
Quality Control of Lipid-Based Formulations by HPTLC
This methodology demonstrates an efficient approach for identity and stability testing of lipids and lipid-based formulations like mRNA vaccines by HPTLC.
Overcoming the Challenges of Bispecific Antibody Characterization Using New Column Chemistries to Detect Product Impurities
Rapid Analysis of mRNA 5’-Capping with High-Resolution LC-MS
Characterization of Antibody-Drug Conjugates (ADC) using 2-Dimension Liquid Chromatography (2D-LC) and Native Mass Spectrometric Technologies
Ensuring Regulatory Compliance and Data Integrity with MassHunter Software Solutions
AN: Optimizing Control of Pump-Related Processes
This white paper will illustrate how integrated pump controllers optimize pump performance by automatically controlling flow or pressure.
Q-RAI Provides Rapid and Sensitive Data Independent Acquisition for Peptide Quantitation
Comprehensive Adeno-Associated Virus Critical Quality Attribute Analysis with Liquid Chromatography-Mass Spectrometry
Automated and simplified two Dimensional LC and High-Resolution MS approach for the identification and characterization of unknown impurity in Mirabegron tablets
Automated Dual Metabolite+Lipid Cell Sample Prep as a Component of an LC/HRMS-based Workflow to Elucidate the Molecular Response to Drug Treatment
Empore C18 StageTips for Peptide Fractionation
This app note demonstrates the application of Empore C18 StageTips to high pH peptide fractionation in global proteomics with enhanced peptide/protein identification.
PATfix™ pDNA analytics for in-process control of linear pDNA production
Application Note: Electrochemical Reduction of Biopharmaceuticals
With a new electrochemical cell, complete reduction of inter- and intra-disulfide bonds in mAbs is achieved. For cystine knots peptides, the sequence coverage was 100%.
Application Note: Hyaluronic acid Characterized by SEC-MALS-IV
The performance of hyaluronic acid is closely tied to its molar mass, intrinsic viscosity, and molecular conformation, quantified absolutely by multi-detector SEC.
Authentic or Synthetic? Discovering Authenticity Markers in Honey
Using sorptive extraction to extract aroma compounds from honey, with automated statistical analysis to uncover differences and determine markers of authenticity
Interview: Ultrapure Type 1 Water Guarantees Best Results for Reliable Analytical QC in the Beverage Industry
Suppressed Anion Chromatography – Analysis of Anions (SI-36 4D)
The SI-36 4D does not require organic solvent to achieve the separation. Gradient conditions and phosphate ions are eluted within 15 minutes, so analysis time is short.
Monovalent and Divalent Cations in Tap Water (Ethylenediamine EDA)
Monovalent and divalent cations in tap water were analyzed by IC YS-50.
Suppressed Anion Chromatography – Analyzing Oxyhalides and Anions (SI-52 4E)
Oxyhalides and anion standards in tap water were analyzed successfully using IC SI-52 4E. This is applicable to analyzing sources like rain, river water, and runoff.
Suppressed Anion Chromatography – Anion Standards (SI-90 4E)
The application successfully separates the 7 typical ions including F-, Cl-, NO2-, Br-, NO3-, PO43-, and SO42-, and it fulfills US EPA Method 300.1 (A) requirements.
Automated Analysis of 37 D/L-Amino Acids Using LC with Fluorescence Detection
This application introduces the automated analysis of fluorescent diastereomers of the proteinogenic D/L-amino acids using derivatizing reagents with chiral structures.
Anion Standards (Comparison of NI-424 and I-524A)
The seven main anions can be separated quickly using the IC NI-424 column. Improvement has been made in the separation of chloride and nitrite ions.
Rapid and High Resolution Fused-Core® Solutions for PFAS Analysis
Fused-Core® Technology benefits PFAS analysis for fast, efficient, and rugged separations which are paramount to environmental analysis.
PFAS Analysis Using Fused-Core® Technology
HALO® PFAS and PFAS Delay columns are application verified columns well suited for challenging environmental sample analysis.