Application Notes

Methadone is a commonly prescribed pain management type drug. As such, patients are monitored on a routine basis.

Monoclonal antibodies (mAbs) form a major class of biologics and recently biosimilars and biobetters are being added to the growing inventory of therapeutics.

Optimizing separation of ionizable compounds in order to find robust conditions has become an important part of method development in liquid chromatography.

Synthetic elastomers have replaced natural rubber to an astonishing degree, and account for more than 70% of the rubber used today.

Two species of spearmint oil (Mentha spicata and Mentha gracilis) are cultivated in the United States.

Starch is used for a variety of industrial and nutritional purposes. Its functional properties are influenced by the ratio and molar masses of its macromolecular constituents, which vary with source, crop year, and climate.

The unique surface chemistry of the FLARE diamond core-shell column combines ionic and hydrophobic separation mechanisms to effectively retain a variety of chemical species in a single run.

Agilent Technologies

Malvern Instruments Ltd.

Bruker Daltonics

Metrohm

Agilent Technologies

Wyatt Technology Corporation

UCT, LLC

The unique surface chemistry of the Flare diamond core-shell column combines ionic and hydrophobic separation mechanisms to effectively retain a variety of chemical species in a single run.

Modified starches are important materials used in many applications including foodstuffs.

High resolution time-of-flight mass spectrometry was used for comprehensive profiling of tobacco plant extracts.

Poly(lactic-co-glycolic acid) (PLGA) is a copolymer based on glycolic acid and lactic acid. The two monomer units are linked together by ester linkages and form linear polyester chains.

Steroids represent a chemically distinct class of hormones with wide-ranging biological functions. Synthetic derivatives of endogenous steroid prototypes are used medically in birth control and in the treatment of asthma, arthritis, inflammation, and osteoporosis.

The dioxin family consists of 210 compounds, of which 17 contain the 2,3,7,8 pattern of chlorination.

Natural and synthetic phenolic compounds have been used in a wide range of applications, from antiseptics and fungicides to food additives.

Pharmaceutical and personal care products (PPCPs) are products used for personal health or cosmetic reasons.

In mass spectrometry instrumentation, the sensitivity and resolution of the instrument is often limited by the detector.

Monoclonal antibodies (mAbs) form a major class of biologics and recently biosimilars and biobetters are being added to the growing inventory of therapeutics.

We have previously shown the ability of a novel stationary phase to separate 55 amino acids without derivatization (LCGC 32(3), 211 [2014]).

A purified polyclonal antibody (IgG) is separated and fully characterized using the Viscotek SEC-MALS 20, allowing calculation of molecular weight and radius of gyration (Rg).

Chiral separations of multi-component natural product mixtures comprised of enantiomers, diastereomers, and unrelated molecules are often difficult to resolve in a single isocratic method.

This application describes a solid phase extraction (SPE) method for EPA method 8141B analytes, including organophosphorus compounds, and triazine herbicides in water.

Alprostadil (Prostaglandin E1) is a drug that has vasodilation properties and is used to treat erectile dysfunction and other medical conditions.

Hydrophilic interaction liquid chromatography (HILIC) is one of the fastest growing modes of separation, in which any polar chromatographic surface can be used.