5th International Workshop on Electrochemistry–Mass Spectrometry (ELCHEMS5 2019)
The 5th International Workshop on Electrochemistry–Mass Spectrometry (ElCheMS5) will be held 11–12 June 2019 at the University of Münster, Germany, and is hosted by the group of Uwe Karst and Martin Vogel.
The 5th International Workshop on Electrochemistry–Mass Spectrometry (ElCheMS5) will be held 11–12 June 2019 at the University of Münster, Germany, and is hosted by the group of Uwe Karst and Martin Vogel. The topics covered span all instrumental aspects of electrochemistry–mass spectrometry (EC–MS), including fundamentals, novel hardware and software, integration of analytical separation techniques, and miniaturized and on-chip approaches for EC–MS. Current applications of EC–MS will form the second major aspect of the meeting, including the simulation of metabolic and advanced oxidation processes, preparative scale EC–MS, the generation of reactive metabolites and their reaction products, and EC–MS in protein and peptide chemistry. The organizers are expecting to see a continuing trend towards the (semi)-preparative use of EC–MS for the generation of milligram-scale amounts of substances to allow further characterization by nuclear magnetic resonance (NMR) and other spectroscopic techniques. Additionally, the trend towards automated approaches will address the challenge to investigate larger numbers of samples within a reasonable time scale. ElCheMS5 will feature tutorialâstyle lectures by leading experts, ensuring it is an ideal event for novices in the field. Contributed oral and poster presentations by the attendees form the backbone of the workshop, and there is ample time to discuss all presentations. Coffee breaks and a barbecue on the evening of 11 June 2019 with beer, steaks, and bratwurst provide further opportunities to meet the experts in person and to share and acquire knowledge. The intense exchange between academia, instrument manufacturers, and chemical and pharmaceutical industries is another established feature of the meeting, which will be continued. Submissions for oral presentations should be submitted by 20 May 2019, and poster submissions by 1 June 2019 to the following address: ElCheMS2019@wwu.de
Website: www.uni-muenster.de/Chemie.ac/en/karst/workshops/elchems.html
AI and GenAI Applications to Help Optimize Purification and Yield of Antibodies From Plasma
October 31st 2024Deriving antibodies from plasma products involves several steps, typically starting from the collection of plasma and ending with the purification of the desired antibodies. These are: plasma collection; plasma pooling; fractionation; antibody purification; concentration and formulation; quality control; and packaging and storage. This process results in a purified antibody product that can be used for therapeutic purposes, diagnostic tests, or research. Each step is critical to ensure the safety, efficacy, and quality of the final product. Applications of AI/GenAI in many of these steps can significantly help in the optimization of purification and yield of the desired antibodies. Some specific use-cases are: selecting and optimizing plasma units for optimized plasma pooling; GenAI solution for enterprise search on internal knowledge portal; analysing and optimizing production batch profitability, inventory, yields; monitoring production batch key performance indicators for outlier identification; monitoring production equipment to predict maintenance events; and reducing quality control laboratory testing turnaround time.
