Mass Spectrometry

Scientists recently used thermal desorption (TD) and gas chromatography– time-of-flight mass spectrometry (GC×GC-TOFMS) to track per- and polyfluoroalkyl substances (PFAS) emissions from materials used in firefighter gear.

Raquel Gonzalez de Vega of the University of Graz recently spoke to us about her work tracking per- and polyfluoroalkyl substances (PFAS) in ski wax products.

Navin Rauniyar and Xuemei Han of Tanvex Biopharma USA recently discussed how identifying product-related variants through characterization enables the recognition of impurities that compromise the quality and safety of drugs.

Hydrophilic interaction chromatography–mass spectrometry (HILIC-MS) offers a flexible and efficient alternative to ion-pairing reversed-phase liquid chromatography (IP-RPLC) for oligonucleotide analysis, with column selectivity and mobile phase pH being key factors in optimizing retention and detection.

The European Commission's regulation on maximum levels for certain contaminants in food highlights the need for precise and reliable methods to quantify per- and polyfluoroalkyl substances (PFAS) in various food matrices. This article discusses development and validation of a robust method for analyzing 21 PFAS compounds in chicken eggs using solid-phase extraction (SPE) and liquid chromatography–mass spectrometry (LC–MS).

Scientists from Institut de Combustion, Aérothermique, Réactivité et Environnement (ICARE-CNRS) in Orléans, France and Chromatotec in Saint-Antoine, France recently created a new algorithm for detecting volatile organic compounds (VOCs) in ambient air.

As part of our ISC 2024 coverage, we recently interviewed Anneli Kruve of Stockholm University about her scientific background and her presentation about eludicating toxic chemicals' structures using LC/HRMS.

As part of our ISC 2024 coverage, we recently interviewed Amarande Murisier of the University Hospital of Lausanne, Switzerland (CHUV) about her winning the Rising Stars of Separation Science Award for Biopharmaceutcal Analysis and her scientific background.

Here is some of the most popular content posted on LCGC International this week.

MS-SMART integrates three intelligent algorithms: automatic mining of diagnostic ions, rapid filtration of alkaloids from untargeted MS/MS data, and structural recommendations for filtered components.

ETHZ and Agroscope scientists tested a new means of analysis against secondary electrospray ionization (SESI) coupled to high-resolution-mass spectrometry (HRMS) for exhaled breath analysis.

Universidad Católica del Maul scientists reviewed advancements made in using machine learning and MALDI-TOF-MS for predicting antimicrobial resistance in different materials.

Supercritical fluid extraction (SFE) was combined with supercritical fluid chromatography (SFC) hyphenated to mass spectrometry (MS) to analyze plastic additives that could be transferred into the environment from laboratory gloves.

Here is some of the most popular content posted on LCGC International this week.

Webinar Date/Time: Wednesday, October 23rd, 2024 Morning Session: 14:30 pm BST | 9:30 am EDT | 15:30 pm CEST Afternoon Session: 16:30 pm BST | 11:30 am EDT | 17:30 pm CEST Thursday, October 24th, 2024 Morning Session: 14:30 pm BST | 9:30 am EDT | 15:30 pm CEST Afternoon Session: 16:10 pm BST | 11:10 am EDT | 17:10 pm CEST

The 2024 Gulf Coast Conference will include a variety of presentations on chromatography. This article features a sampling of some upcoming sessions.

Scientists from Tianjin universities and Cleveland State University investigated how to characterize a potent chemical compound in Platycodon grandiflorus roots.

Soochow University scientists recently reviewed how HILIC breakthroughs have helped with handling glycopeptides and glycans.

In this article, we review some key considerations for chromatographic technique selection and method development across the full drug process.

Stockholm University scientists used liquid chromatography coupled with high-resolution mass spectrometry (LC-HRMS) to characterize recycled textile products and detect harmful chemicals.

Scientists from the Guangdong Academy of Sciences and the Guangdong University of Technology used nanospray laser-induced plasma ionization mass spectrometry (nLIPI-MS) to analyze broad polarity organic pollutants under ambient and open-air conditions.

Here is some of the most popular content posted on LCGC International this week.

Lausanne University Hospital scientists recently tested ultrahigh-performance supercritical fluid chromatography hyphenated to tandem mass spectrometry (UHPSFC–MS/MS) for detecting urinary endogeneous steroids.

University of Saskatchewan scientists analyzed phosphorus compounds in soil using two-dimensional ion chromatography-tandem mass spectrometry (2D-IC-MS/MS).

Korea Food Research Institute scientists combined QuEChERS extraction with ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC–MS/MS) to analyze vitamins D and K in yogurt.

Scientists from Henan Normal University and Yellow River Conservancy Technical Institute used UHPLC–MS/MS to characterize quaternary phosphonium compounds (QPCs) and phosphine oxides (POs) in water and solid samples.

Here are the top five articles published on LCGC International this week.

Soochow University scientists used a mass spectrometry (MS)-based system to help better understand the structure of Sulodexide.

A recent study analyzed nearly 100 CBD products to test the accuracy of advertised cannabinoid content.