ISC 2024: An Interview with Amarande Murisier

During the 34th International Symposium on Chromatography, which takes place from October 6–10, 2024 in Liverpool, UK, various scientists are honored for their contributions to the analytical chemistry community. This year, LCGC International was honored to present Amarande Murisier our Rising Stars of Separation Science Award for Outstanding Achievement in Biopharmaceutical Analysis, sponsored by Agilent Technologies.

Amarande Murisier obtained her Ph.D. from the University of Geneva in 2022. Her research focuses on improving liquid chromatographic (LC) methods, which are essential tools for separating, identifying, and quantifying complex biological molecules. Specifically, her work aimed at working to techniques such as size exclusion chromatography (SEC) and ion exchange chromatography (IEC), improving efficiency by coupling with mass spectrometry (MS) for precise protein characterization.

She also made a major contribution to pioneering work in developing ultra short columns for biopharmaceutical analysis. In 2023, she joined the clinical pharmacology group at the University Hospital of Lausanne, Switzerland (CHUV), developing, among other things, techniques for quantifying antibodies in the patient’s blood. Since September, she serves as an Analytical Lab Manager at Merck, in charge of a team of scientists and technicians dedicated to method development and routine assay analysis to support early-phase pipeline. Murisier has published several fundamental papers on separation techniques for biopharmaceuticals, as well as application-oriented articles.

As part of our conference coverage, we sat down with Murisier to learn more about her background and what drives her interest in analytical chemistry.

In this interview, we asked the following questions:

• Congratulations on winning the Rising Stars of Separation Science Award for Biopharmaceutcal Analysis! When did you first encounter chromatography? What attracted you to the subject?
• Can you tell us more about your PhD thesis?
• Who has inspired you throughout your career?
• What is your favorite scientific paper?
• What chromatographic techniques have you worked with?
• Liquid chromatography–mass spectrometry (LC–MS) has become a popular technique in various laboratories, including QC laboratories. What is your opinion on this trend?
• You have taught practical analytical chemistry at the Universities of Geneva and Lausanne. Do you think these courses are important for life science students?
• What do you think the future holds for biopharmaceutical analysis laboratories?

For more details about Murisier's award, you can read more here.

Reference

(1) Alexandre Goyon. Genentech 2024. https://www.gene.com/scientists/our-scientists/alexandre-goyon (accessed 2024-10-7)