Liquid Chromatography (LC/HPLC)

In a new study, scientists reflected on different advancements made in extracting, purifying, and quantifying kaempferol, a natural product present in various sources.

In this installment of “LC Troubleshooting,” we describe an artifact that can arise because of compound degradation during the transfer of fractions of the first dimension (1D) column effluent to the 2D separation.

Here is some of the most popular content posted on LCGC International this week.

This “Column Watch” installment presents many of the highlighted topics and trends observed at the 52nd International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC 2024).

Stockholm University scientists used liquid chromatography coupled with high-resolution mass spectrometry (LC-HRMS) to characterize recycled textile products and detect harmful chemicals.

In this LCGC Blog, Daipayan Roy and Muhammed Qamar Farooq of Amgen discuss the history and impact of supercritical fluid chromatography (SFC) throughout the years.

Here is some of the most popular content posted on LCGC International this week.

Karlstad University scientists modeled pH-dependent retention and competitive adsorption of solutes using mixed-mode and reversed-phase liquid chromatography.

Waters Corporation scientists recently examined how different mobile and stationary phases affect small interfering RNA (siRNA) duplex stability in liquid chromatography.

Edinburgh Napier University and University of Helsinki scientists recently compared two techniques for their effectiveness in assessing drug passage through respiratory mucosa.

Korea Food Research Institute scientists combined QuEChERS extraction with ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC–MS/MS) to analyze vitamins D and K in yogurt.

Scientists from Gansu Agricultural University recently used high-performance liquid chromatography (HPLC) to quantify 16 polyphenols in tomato fruits.

Scientists from Henan Normal University and Yellow River Conservancy Technical Institute used UHPLC–MS/MS to characterize quaternary phosphonium compounds (QPCs) and phosphine oxides (POs) in water and solid samples.

Here are the top five articles published on LCGC International this week.

Soochow University scientists used a mass spectrometry (MS)-based system to help better understand the structure of Sulodexide.

At HTC-18 in Leuven, Executive Editor of LCGC International, Alasdair Matheson, spoke to Brett Paull from the University of Tasmania and HyTECH about his talk entitled: “Analytical Performance and Disruptive Potential of Fully Portable Portable and Field Deployable LC–MS Technology.”

National Institute of Pharmaceutical Education and Research (NIPER) scientists recently highlighted LC–MS’s use in improving drug modalities.

Scientists from the Federal University of Santa Catarina reviewed recent advancements made in the chromatographic analysis of endocannabinoids and phytocannabinoids in biological samples.

Here are the top five articles published on LCGC International this week.

In this installment of “LC Troubleshooting,” we discuss strategies that can be used to minimize the likelihood of compound degradation in the isolation process.

Here are the top five articles published on LCGC International this week.

Steven Ray Wilson and Hanne Røberg-Larsen of the University of Oslo recently discussed the practical application and advantages of their FDA-validated research to analyse small molecule drugs and their metabolites in organoid/organ-on-chip systems that serve as alternatives to animal models.

In a new study, scientists developed a new high-performance liquid chromatography (HPLC) system to optimize miniaturized liquid chromatography (LC).

Dr. Harisingh Gour University scientists recently used micellar liquid chromatography to test how effectively different washing techniques remove insecticides.

Here are the top five articles published on LCGC International this week.

Scientists from the Institute of Environmental Assessment and Water Research developed and optimized a method for determining various pesticides in human urine.

Northwestern Polytechnical University scientists recently tested a new approach for integrating micro-lenses and slits into portable liquid chromatography (LC) systems.

Tianjin Centers for Disease Control and Prevention scientists used chromatography techniques to determine bisphenol analogues (BPs) in human urine.

Dalian Maritime University scientists recently used high-performance liquid chromatography tandem triple quadrupole mass spectrometry HPLC-MS/MS to help detect amphetamine-type drugs in water.

Scientists from Università Politecnica delle Marche reported on baseline separation of isotopologoues of some amphetamine (AMP) derivatives on achiral and polysaccharide-based chiral columns.