Identifying Fraudulent Saffron Using UHPLC–HRMS/MS and Metabolomics
April 11th 2017Researchers from the University of Chemistry and Technology in Prague, Czech Republic, have developed a saffron authentication process based on ultrahigh-performance liquid chromatography coupled to high resolution tandem mass spectrometry (UHPLC–HRMS/MS) and multivariate data analysis.
Shimadzu Launches European Innovation Center
April 11th 2017Shimadzu Corporation has opened a new European Innovation Center in Duisburg, Germany. The new facility will merge Shimadzu’s state-of-the-art analytical technologies with prominent topics, market expertise, and scientific research guided by some key opinion leaders.
Targeting Specific Matrix Interferences for Sample Preparation
April 11th 2017This article describes the evolution of traditional solid-phase extraction (SPE) into new techniques that are customized to the characteristics of specific matrices, including the removal of β-glucuronidase from urine samples and the removal of phospholipids and proteins from plasma samples.
41st International Symposium on Capillary Chromatography & 14th GC×GC Symposium
April 11th 2017The 41st International Symposium on Capillary Chromatography (ISCC) and the 14th GC×GC Symposium will be held in Fort Worth, Texas, USA, on the 14–19 May 2017. This preview offers a flavour of what to expect.
The LCGC Blog: Relating Analyte Properties to HPLC Column Selectivity – On the Road to Nirvana
April 4th 2017As I’ve written previously, our Nirvana in HPLC column selection would be to enter the structures of our analytes and have a database tell us the column and mobile phase conditions that we should use to carry out the separation successfully. Although I know of several groups who are working on this, in practice we are still a long way from realizing this goal.
Count the Cost, Part 2: Increasing Resolution by Increasing Retention
April 1st 2017We will discover how to find the “sweet spot” in terms of retention for a liquid chromatographic separation as well as how much retention change can be expected for a selected change in organic mobile-phase percentage or column temperature.
Identifying Fraudulent Saffron Using UHPLC–HRMS/MS and Metabolomics
March 14th 2017Researchers from the University of Chemistry and Technology in Prague, Czech Republic, have developed a saffron authentication process based on ultrahigh-performance liquid chromatography coupled to high resolution tandem mass spectrometry (UHPLC–HRMS/MS) and multivariate data analysis.
Identifying Greek Drug Consumption Using LC–MS/MS
March 7th 2017Researchers from the National and Kapodistrian University of Athens have used liquid chromatography with tandem mass spectrometry (LC–MS/MS) to understand changes in licit and illicit drug consumption patterns following the major socioeconomic changes Greece has experienced.
Ultrafast Gas Chromatography: Key Considerations in Method Development
March 7th 2017Ultrafast gas chromatography (UFGC) offers analysis times 5–20 times faster than conventional GC, with comparable sample capacity and resolution. These factors along with greatly reduced energy consumption make UFGC a valuable approach to explore in many application areas. This article describes the principles and practical uses of ultrafast GC and the key considerations in method development using this technique.