Author
Latest:
Microchip Electrophoresis and the Analysis of Polymerase Chain Reaction ProductsThe author compares chip-based electrophoretic methods with existing methods and competitors.
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Intelligent Automation of LC–MS Analysis for the Characterization of Compound LibrariesThis article reports an approach to applying intelligent automation for high-throughput LC}MS analysis of compound libraries using Microsoft Visual Basic software.
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GC–MS Analysis of Heart-Cut Fractions During Evolved Gas Analysis of Polymeric MaterialsThe authors describe the characterization of polymers and additives using a novel heart-cut evolved gas analysis GC–MS method.
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GC–MS Analysis of Heart-Cut Fractions During Evolved Gas Analysis of Polymeric MaterialsThe authors describe the characterization of polymers and additives using a novel heart-cut evolved gas analysis GC–MS method.
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An Efficient Approach to Column Selection in HPLC Method DevelopmentThe authors present an efficient, informed approach to HPLC column selection based upon complementary decisions regarding bonded-phase and particle physical characteristics.
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GC–MS Analysis of Heart-Cut Fractions During Evolved Gas Analysis of Polymeric MaterialsThe authors describe the characterization of polymers and additives using a novel heart-cut evolved gas analysis GC–MS method.
Latest:
GC–MS Analysis of Heart-Cut Fractions During Evolved Gas Analysis of Polymeric MaterialsThe authors describe the characterization of polymers and additives using a novel heart-cut evolved gas analysis GC–MS method.
Latest:
GC–MS Analysis of Heart-Cut Fractions During Evolved Gas Analysis of Polymeric MaterialsThe authors describe the characterization of polymers and additives using a novel heart-cut evolved gas analysis GC–MS method.
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Operational and Performance QualificationGuest authors discuss equipment qualification for good laboratory and manufacturing practices compliance.
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Operational and Performance QualificationGuest authors discuss equipment qualification for good laboratory and manufacturing practices compliance.
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Uncovering Deficiencies in Mass Balance Using HPLC with Chemiluminescence Nitrogen-Specific DetectionThe author describes using HPLC with chemiluminescence nitrogen-specific detection and aperometric detection to determine organic impurities in a tedisamil dihydrochloride drug substance.
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GC–MS Analysis of Heart-Cut Fractions During Evolved Gas Analysis of Polymeric MaterialsThe authors describe the characterization of polymers and additives using a novel heart-cut evolved gas analysis GC–MS method.
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High-Throughput Separations Using Multiplexed Capillary Electrophoresis with Laser-Induced Fluorescence DetectionThe authors evaluate the performance of multiplexed 96-lane CE with laser-induced fluorescence detection for high-throughput separation–based assays using fluorescein isothiocyanate as a model compound and fluorescein as an internal standard.
Latest:
High-Throughput Separations Using Multiplexed Capillary Electrophoresis with Laser-Induced Fluorescence DetectionThe authors evaluate the performance of multiplexed 96-lane CE with laser-induced fluorescence detection for high-throughput separation–based assays using fluorescein isothiocyanate as a model compound and fluorescein as an internal standard.
Latest:
High-Throughput Separations Using Multiplexed Capillary Electrophoresis with Laser-Induced Fluorescence DetectionThe authors evaluate the performance of multiplexed 96-lane CE with laser-induced fluorescence detection for high-throughput separation–based assays using fluorescein isothiocyanate as a model compound and fluorescein as an internal standard.
Latest:
High-Throughput Separations Using Multiplexed Capillary Electrophoresis with Laser-Induced Fluorescence DetectionThe authors evaluate the performance of multiplexed 96-lane CE with laser-induced fluorescence detection for high-throughput separation–based assays using fluorescein isothiocyanate as a model compound and fluorescein as an internal standard.
Latest:
High-Throughput Separations Using Multiplexed Capillary Electrophoresis with Laser-Induced Fluorescence DetectionThe authors evaluate the performance of multiplexed 96-lane CE with laser-induced fluorescence detection for high-throughput separation–based assays using fluorescein isothiocyanate as a model compound and fluorescein as an internal standard.
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Validation of Bioanalytical Capillary Gel Electrophoresis Methods for the Determination of OligonucleotidesGuest authors describe how this validation is performed routinely in their laboratory.
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On the Interpretation of GC × GC DataThe authors present their observations from developing data-handling software for GC × GC separations.
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Fused-Silica Capillary — The Story behind the TechnologyGuest author Steve Griffin identifies the fundamental problems in capillary manufacturing techniques that cause capillary defects and suggests some corrective actions.
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Validation of Bioanalytical Capillary Gel Electrophoresis Methods for the Determination of OligonucleotidesGuest authors describe how this validation is performed routinely in their laboratory.
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Validation of Bioanalytical Capillary Gel Electrophoresis Methods for the Determination of OligonucleotidesGuest authors describe how this validation is performed routinely in their laboratory.
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Validation of Bioanalytical Capillary Gel Electrophoresis Methods for the Determination of OligonucleotidesGuest authors describe how this validation is performed routinely in their laboratory.
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Validation of Bioanalytical Capillary Gel Electrophoresis Methods for the Determination of OligonucleotidesGuest authors describe how this validation is performed routinely in their laboratory.
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Practical Considerations of the Influence of Organic Modifiers on the Ionization of Analytes and Buffers in Reversed-Phase LCThis article provides theoretical background, experimental data, and practical considerations about the effects of organic modifiers on analyte ionization in reversed-phase LC.
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The Retention Behavior of Reversed-Phase HPLC Columns with 100% Aqueous Mobile PhaseThe authors studied the retention behavior of reversed-phase HPLC columns under 100% aqueous mobile-phase conditions.
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The Retention Behavior of Reversed-Phase HPLC Columns with 100% Aqueous Mobile PhaseThe authors studied the retention behavior of reversed-phase HPLC columns under 100% aqueous mobile-phase conditions.
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Practical Considerations of the Influence of Organic Modifiers on the Ionization of Analytes and Buffers in Reversed-Phase LCThis article provides theoretical background, experimental data, and practical considerations about the effects of organic modifiers on analyte ionization in reversed-phase LC.
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The Retention Behavior of Reversed-Phase HPLC Columns with 100% Aqueous Mobile PhaseThe authors studied the retention behavior of reversed-phase HPLC columns under 100% aqueous mobile-phase conditions.
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Ion Mobility Spectrometry (IMS): How It Works and Its Use in BiotechnologyIMS is a valuable tool for biopharmaceutical analysis. Two formats in particular have proven useful: cyclic IMS and structures for lossless manipulations (SLIM).
