The guest authors present a strategy for validating a capillary isoelectric focusing method intended to quantitate impurities in a protein drug substance.
The guest authors present a strategy for validating a capillary isoelectric focusing method intended to quantitate impurities in a protein drug substance.
This article examines the role that multidimensional chromatography systems will play in high-throughput proteomics.
Part II of this series describes different ways electrolytes can be buffered while maintaining compatibility with indirect detection.
Part II of this series describes different ways electrolytes can be buffered while maintaining compatibility with indirect detection.
The FDA recently updated its 1987 guidelines for submitting samples and analytical data for method validation — a document that affects all analytical chemists working in the pharmacrutical industry. This article highlights the agency's recommendations of how to report and validate analytical data in all new drug applications.
The FDA recently updated its 1987 guidelines for submitting samples and analytical data for method validation — a document that affects all analytical chemists working in the pharmacrutical industry. This article highlights the agency's recommendations of how to report and validate analytical data in all new drug applications.
The FDA recently updated its 1987 guidelines for submitting samples and analytical data for method validation — a document that affects all analytical chemists working in the pharmacrutical industry. This article highlights the agency's recommendations of how to report and validate analytical data in all new drug applications.
The FDA recently updated its 1987 guidelines for submitting samples and analytical data for method validation — a document that affects all analytical chemists working in the pharmacrutical industry. This article highlights the agency's recommendations of how to report and validate analytical data in all new drug applications.
This article examines the role that multidimensional chromatography systems will play in high-throughput proteomics.
This article examines the role that multidimensional chromatography systems will play in high-throughput proteomics.
Norberto Guzman and Ron Majors look at three areas in which progress has been made in improving concentration limits of detection for CE and CE microchip techniques: preconcentration methods, detector enhancements, and derivatization methods to improve separation selectivity and to enhance detection.
The FDA recently updated its 1987 guidelines for submitting samples and analytical data for method validation — a document that affects all analytical chemists working in the pharmacrutical industry. This article highlights the agency's recommendations of how to report and validate analytical data in all new drug applications.
The FDA recently updated its 1987 guidelines for submitting samples and analytical data for method validation — a document that affects all analytical chemists working in the pharmacrutical industry. This article highlights the agency's recommendations of how to report and validate analytical data in all new drug applications.
The FDA recently updated its 1987 guidelines for submitting samples and analytical data for method validation — a document that affects all analytical chemists working in the pharmacrutical industry. This article highlights the agency's recommendations of how to report and validate analytical data in all new drug applications.
The authors focus on problems that may occur when converting conventional methods to LC–MS.
The FDA recently updated its 1987 guidelines for submitting samples and analytical data for method validation — a document that affects all analytical chemists working in the pharmacrutical industry. This article highlights the agency's recommendations of how to report and validate analytical data in all new drug applications.
The FDA recently updated its 1987 guidelines for submitting samples and analytical data for method validation — a document that affects all analytical chemists working in the pharmacrutical industry. This article highlights the agency's recommendations of how to report and validate analytical data in all new drug applications.
Guest author Barry Lesnik attempts to clarify the multiple uses of the term validation in environmental analysis.
This installment of "Directions in Discovery" describes experiments performed to optimize a standard quality-control method for protein purity evaluation using reducing capillary gel electrophoresis.
This article examines the role that multidimensional chromatography systems will play in high-throughput proteomics.
This installment of "Directions in Discovery" describes experiments performed to optimize a standard quality-control method for protein purity evaluation using reducing capillary gel electrophoresis.
The FDA recently updated its 1987 guidelines for submitting samples and analytical data for method validation — a document that affects all analytical chemists working in the pharmacrutical industry. This article highlights the agency's recommendations of how to report and validate analytical data in all new drug applications.
The FDA recently updated its 1987 guidelines for submitting samples and analytical data for method validation — a document that affects all analytical chemists working in the pharmacrutical industry. This article highlights the agency's recommendations of how to report and validate analytical data in all new drug applications.
This month's column looks at methods for preparing calibration standards for VOC analysis.
Part II of this series describes different ways electrolytes can be buffered while maintaining compatibility with indirect detection.
This article examines the role that multidimensional chromatography systems will play in high-throughput proteomics.
This article examines the role that multidimensional chromatography systems will play in high-throughput proteomics.
This article describes a case study in which forensic chemical analyses were conducted to determine the liability for the release of an unknown petroleum product into a river.
This article describes a case study in which forensic chemical analyses were conducted to determine the liability for the release of an unknown petroleum product into a river.