Application Notes

The Ultivo LC/TQ based method works for the 6 nitrosamines listed by the FDA and the simultaneous detection of six other potentially mutagenic nitrosamine impurities.

Demonstrates the analysis of 22 different active pharmaceutical ingredients (APIs) for their purity in an open-access environment using mass detection

A fast and reliable method for comparison of related impurities in a brand and a generic over-the-counter (OTC) acetaminophen drug.

-A systematic framework for analyte extraction and solubilization from typical pharmaceutical matrices -Potential pitfalls of commonly used sample-preparation approaches -Experimental design for better sample preparation

Method development for simultaneous analysis of ultrashort-chain, alternative, and legacy PFAS.

This note looks at the analysis of N-nitrosamines in rubber teats, soothers, and toys, with specific focus on babies and young children under UK method BS EN 71-12:2016.

1. How B-One recombinant ß-glucuronidase will help simplify sample prep 2. Detailed protocol and tips to achieve the highest enzymatic performance 3. Complimentary information for improving results

Extraction of pesticides from foods can be a daunting task. QuEChERS have been the industry standard for years but have many shortcomings

Single-step water mitigation and extraction of pesticides from wet foods 9 min automated extraction of pesticides with results comparable to QuEChERS UPLC MS/MS comparative analysis of extracted pesticide residue from wet foods

Learn about aggregate and charge-variant analysis using native-mode MS Understand the fundamentals in SEC and IEX for biotherapeutic characterization Learn the effect of mobile-phase conditions and chromatographic parameters in aggregate analysis by native SEC

This application note demonstrated the correlation coefficient (R2) > 0.99 from 26 fragrance compounds analysed by a CDS Analytical dynamic headspace module with PAL.

• Solutions to laboratory-weighing challenges require the latest technology. • New balances offer custom hardware, software, and connectivity solutions.

• Extraction of THC, THCA, CBD, CBDA, and CBN from hemp flower in minutes • Low temperature extraction of cannabinoids to eliminate acid formation • Cannabinoid profile extraction without use of cleanup sorbents

• Extract antioxidants and slip additives from plastic matrices • Rapid automated extraction of plastics • Analysis of additives from plastics after automated extraction

• Rapid alternative to QuEChERS for pesticide analysis • Automated extraction of pesticide mixture from spices • UPLC MS/MS analysis of extracted pesticide residue

• Automated extraction of pesticide mixture from cannabis flower • Analysis by GC and LC of over 300 extracted pesticides • Alternative to QuEChERS for cannabis pesticide analysis

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- ADCs can be analyzed using various methods other than the traditional HIC. - New chromatographic materials expand analytical techniques for APOC

• Methods for sports doping control using high resolution mass spectrometry • Using HRMS, one GC–MS and LC–MS method offers efficient, accurate screening

-GC×GC offers dramatic improvements over traditional gas chromatography for the analysis of complex mixtures in numerous applications -The power and utility of GC×GC technology -The need for more advanced and novel stationary phases for gas-chromatographic columns

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Extraction of pesticides from foods can be a daunting task. QuEChERS have been the industry standard for years but have many shortcomings including being time consuming and manual. A new, rapid alternative to QuEChERS, that performs a single-step-automated extraction and water removal, is taking the challenge out of food sample prep.