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Transfer of an EP method for Impurity Analysis of Chlorhexidine
This application note demonstrates the transfer of analytical HPLC methods from an Agilent 1260 Infinity LC system to the Vanquish Core HPLC system.
Transfer Method for Impurity Analysis of Chlorhexidine
This application note demonstrates the transfer of analytical HPLC methods from a Waters Alliance HPLC system to the Vanquish Core HPLC system.
U/HPLC Workflow Solution for Biosimilar Characterization
The molecular similarity between Humira® and Yervoy® biosimilars and the corresponding innovator reference products is examined using analytical SEC, RPC and HIC.
Eliminate the Impact of Instrument-Related PFAS Interferences
· Traps and “delays” system-related PFAS, preventing interference · Allows accurate identification and quantitation of trace-level PFAS · Highly retentive-no breakthrough even with extended equilibration times
Modern Instruments for Improved Environmental Analysis
-High-efficiency source in GC/MS: using sensitivity to enhance productivity -Simultaneous analysis of volatile organic compounds and 1,4-dioxane -Industry challenges and the importance of reliable, robust technology
Case Study: Molecules of Interest
A focus on research scientist and analytical chemist, Diana Jaeger, analyzing samples using LC/TQ for River Stone Biotech, a new player in synthetic biology.
Glyphosate (Roundup) in drinking water
A simple and sensitive method is presented for the direct analysis of Glyphosate and AMPA in drinking water without sample derivatization or pre-concentration.
PFASs in Drinking Water Using Solid-Phase Extraction
This application note outlines a simple SPE procedure for the extraction of 26 diverse per- and polyfluoroalkyl substances (PFASs) in drinking water.
Optimize Selectivity Using Fused-Core® Particles
This white paper discusses the advantages of using fast, efficient HALO® Fused-Core® Technology columns and manipulating selectivity to quickly develop methods, for fast high efficiency LC and LCMS separations.
Easier-Than-Ever Preparation of Standards
The evaluation of a system for automatic preparation and documentation of 100% comparable standards
Separating Sugar Isomers by HPLC
Simple sugars ribose and xylose (are easily and quickly separated on a very stable amide column using high acetonitrile concentration in the mobile phase.
Part 2: A Conversation with Monica Cahilly: Current Perspective for CGxP Compliance
• Special considerations when updating software • Data integrity challenges in the cloud environment • Implications of moving to the cloud with respect to audits
Part 3: A Conversation with Monica Cahilly: Current Perspective for CGxP Compliance
• Validating custom calculations • The importance of a second-person review and locking data • How to compile a data-integrity plan · · ·
Trapped Ion Mobility Combined with LC–HRMS
This RAFA 2019 winner of the Best Poster Award, reviews the identification and characterization of secoiridoids isomers found in Greek extra virgin olive oil (EVOO).
Lab Coping Helium Shortage
Note discusses how labs are coping with the worldwide helium shortage.
Fungus Among Us – Aflatoxin Determination
The metabolites from an infection of the fungus, Aspergillus flavus in foods are known to be toxic to human life, infected food needs to be identified.
Discovery of Biomarkers in Breath
Study demonstrating the development of an analytical platform based upon TD–GC×GC–TOF MS and showing its application to the collection and analysis of breath samples
In-Well Hydrolysis Using UCT’s Refine™ Ultra-Filtration Technology
Analysis of Mycotoxins in Hemp and Hemp-Containing Edible Products
Improving Food Safety Analysis with LC/Q-TOF
* Analysis of pesticides in complex food matrices * Nontargeting screening for food adulterants/contaminants * Food authenticity testing with LC/Q-TOF
3-MCPD and Glycidol in Edible Oils
Automated GC/MS determination of 3-MCPD and glycidol in edible oils. Evaporation step helps reach required LODs with standard MSD and removes excess derivatization reagent for improved stability.
Assessment of µPAC™ capLC Column Performance
PharmaFluidics introduces a new µPAC™ capLC column that offers unprecedented performance and that given its low back pressure can be used up to flow rates of 15 µL/min.
Oligonucleotide Analysis Using a Polymer-Based Diol Column
Analysis of Tetrahydrocannabinol Vape Oils Using Pyroprobe by Thermal Extraction
This application note adopted the Full Evaporation Technique (FET) to analyze the solvent residual, based on California Residual Solvents Category, in cannabis oil.
SEC-MALS Analysis of Linear and Branched Synthetic Amyloses
Analysis of Oligonucleotides by SEC
Rapid, Automated Extraction of Pesticides from a Strawberry CRM
Utilizing Automated SPE to Improve the Recovery of Semivolatile Compounds in Compliance with EPA Method 8270
Quantifying CQAs of gene therapy vectors
This note describes how SEC-MALS-UV-RI analysis quantifies multiple critical quality attributes of AAV viral vectors, including concentration/titer, aggregation and empty:full ratio.
LIMS Tackles Data Integrity Challenges
*The challenges of temporary data *How dynamic data auditing helps compliance with data integrity standards *What to look for in a LIMS platform for 21 CFR Part 11 and Annex 11 compliance