Application Notes

The evaluation of a system for automatic preparation and documentation of 100% comparable standards

Simple sugars ribose and xylose (are easily and quickly separated on a very stable amide column using high acetonitrile concentration in the mobile phase.

• Special considerations when updating software • Data integrity challenges in the cloud environment • Implications of moving to the cloud with respect to audits

• Validating custom calculations • The importance of a second-person review and locking data • How to compile a data-integrity plan · · ·

This RAFA 2019 winner of the Best Poster Award, reviews the identification and characterization of secoiridoids isomers found in Greek extra virgin olive oil (EVOO).

Note discusses how labs are coping with the worldwide helium shortage.

The metabolites from an infection of the fungus, Aspergillus flavus in foods are known to be toxic to human life, infected food needs to be identified.

Study demonstrating the development of an analytical platform based upon TD–GC×GC–TOF MS and showing its application to the collection and analysis of breath samples

* Analysis of pesticides in complex food matrices * Nontargeting screening for food adulterants/contaminants * Food authenticity testing with LC/Q-TOF

Automated GC/MS determination of 3-MCPD and glycidol in edible oils. Evaporation step helps reach required LODs with standard MSD and removes excess derivatization reagent for improved stability.

PharmaFluidics introduces a new µPAC™ capLC column that offers unprecedented performance and that given its low back pressure can be used up to flow rates of 15 µL/min.

This application note adopted the Full Evaporation Technique (FET) to analyze the solvent residual, based on California Residual Solvents Category, in cannabis oil.

This note describes how SEC-MALS-UV-RI analysis quantifies multiple critical quality attributes of AAV viral vectors, including concentration/titer, aggregation and empty:full ratio.

*The challenges of temporary data *How dynamic data auditing helps compliance with data integrity standards *What to look for in a LIMS platform for 21 CFR Part 11 and Annex 11 compliance

Using Full Evaporation Technique (FET) to analyze the solvent residual (California Residual Solvents Category I and II) in cannabis oil by a CDS dynamic headspace module

Solid-phase extraction (SPE) is a powerful technique for LC­–MS analysis. SPE offers benefits for various solutes from a wide range of samples. Modern SPE systems can remove unwanted compounds and streamline methods.

- A data life cycle for chromatography - What is GDocP? - Understanding data integrity metrics for chromatography

Essential oils have been a staple of the food, fragrance, and health markets for many years. Owing to their unique composition, essential oils can be used for a variety of applications.

This application note showcases the development of two methods using photodiode array detection (PDA) to separate three isomers of tocopherol (vitamin E).