Application Notes

Nitrogen was used as the carrier gas instead of helium Trace amounts of thiophene were easily measured SCD provided excellent sensitivity and selectivity

What you will learn: - New workflow aims to ameliorate the difficulties of water analysis - Incorporates risk assessments/cheminformatics to prioritize suspect chemicals - Strategy increases confidence in the results.

What you will learn: - Automated extraction method achieves higher recoveries - Steps involved in QuEChERs vs. EDGE method

-Automated SIFT–MS increases productivity for thermal desorption tube analysis. -Case studies show that TD–SIFT–MS improves analysis for several applications.

This application note demonstrates a multistep thermal extraction study on tetrahydrocannabinol (THC) vape oils.

Pickering Laboratories developed an easy and sensitive method to analyze aflatoxins B1, B2, G1, G2, and ochratoxin A in hemp and hemp-containing edible products. Mycotoxins are isolated using immunoaffinity clean-up columns and analyzed with fluorescence detection. To increase sensitivity of aflatoxins B1 and G1, an in-line photochemical reactor (UVETM) is installed before the detector. This method utilizes standard HPLC equipment and allows laboratories to easily determine these mycotoxins at low ppb levels.

The oligonucleotide therapeutics field has seen remarkable progress over the last few years and oligonucleotides are increasingly recognized as potential therapeutic agents for a variety of diseases. Here we describe the ability of ultra-high pressure size exclusion chromatography (SEC) to distinguish N and N-1 oligonucleotide species.

-Overview of international guidances for data integrity -Insight into PIC/S guidances -Challenges of managing documentation

• Solutions for comparing innovator and biosimilar mAbs • Biosimilar case studies

• Data security in electronic versus paper environments • Division of responsibilities between users and vendors • Specific payment plans can provide advantages to meet financial goals.

-How to translate methods, maximize resolution, and comply with USP -Optimizing HPLC/UHPLC method development workflows -Column coupling can provide improved sample detail and high peak capacities

Automated QuEChERS clean-up of hemp oil extracts combined with liquid introduction and PTV-GC–MS determination of pesticides leads to improved throughput and low LOQs.

This application note adopted the Full Evaporation Technique (FET) to analyze the solvent residual, based on California Residual Solvents Category, in cannabis oil.