Liquid Chromatography (LC/HPLC)

This report shows the steps involved in the development of a new polymethyl methacrylate (PMMA) calibration standard for polar organic GPC applications.

The Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy, an event that features the newest applications and technologies in the chromatography industry, have announced the 2008 Pittsburgh Conference Memorial National College Grants (PCMNCG) Program.

Eksigent, a developer of advanced low-flow fluid delivery liquid chromatography technologies, announced distribution agreements with three companies in Europe for sales and service of the company's high performance liquid chromatography (HPLC) and liquid chromatography (LC) product lines.

Leipziger Messe, organisers of L.A.B. - the trade fair and conference devoted to analysis, bio and laboratory equipment - have announced that the show will host 88 exhibitors from countries including the UK, US, France, Italy, Finland, the Netherlands, and Germany. L.A.B. takes place from 2-4 October 2007 at ExCeL London.

Ronald E. Majors, LCGC North America columnist and Senior Chemist for the Columns and Supplies Division of Agilent Technologies, Inc., has been awarded the 2007 Martin Gold Medal by the Chromatographic Society in the United Kingdom for outstanding contributions to the chromatography field.

Waters Corporation (Milford, Massachusetts) and Lambda Therapeutic Research Ltd (Mumbai, India) recently announced a joint cooperative agreement that provides innovative analytical laboratory equipment designed to enhance research quality service and business solutions for Lambda and its clients.

Science Daily, a website that features news revolving around the sciences, has published an article that describes new chromatographic techniques for the analysis of pesticides and antibiotics in food and beverage samples.

Applied Biosystems (Foster City, California) recently announced three new value-added services for laboratories that are utilizing Applied Biosystems/MDS SCIEX mass spectrometry (MS) instrument systems as part of an overall workflow solution.

Nanostream, provider of products and services that increase productivity in laboratories at pharmaceutical and biotech companies, extends its global reach to Europe by establishing a sales and support office in The Netherlands.

Biodiesel Magazine has recently posted an article that gives an overview of biodiesel test methods, which includes gas chromatography (GC), infrared spectrometry (IR), and inductively coupled plasma (ICP).

The Victoria Advocate (Victoria, TX) published an article about the random testing of high school student-athletes in the Texas public school system. The article is entitled "No Steroid Test is Foolproof" and focuses on the process of drug testing using gas chromatography-mass spectroscopy (GC-MS).

The Montreal Gazette published an article about the use of analytical techniques in the wine industry. The author discusses the difference between "natural" wines and "industrial" wines that are created with a certain taste profile in mind and with the assistance of gas chromatography.

AC Analytical Controls developed a new chromatographic solution that complies with all ASTM & EN chromatographic test methods listed in biodiesel specifications: the AC all-in-one Biodiesel analyser. Analysis results demonstrate that the AC analyser complies with EN 14103, EN 14105, EN 14106, EN 14110 & ASTM D6584 methods.

Different methods require different strategies.

Cleaning validation is a major analytical application in the pharmaceutical industry. Here, high performance liquid chromatography (HPLC) with charged aerosol detection is compared and contrasted to HPLC with UV detection showing comparable performance and several advantages for charged aerosol detection, especially for analytes that do not contain a chromophore.

In the fourth installment in a series on method development for liquid chromatography (LC), with an emphasis on devloping trouble-free methods quickly. John Dolan started out by considering some of the goals we might have and some method development strategies.

Columnist Ron Majors covers some of the highlights of HPLC 2007 including honorary sessions, best poster awards, and the latest developments in HPLC column technology.

Liquid chromatography (LC) separations performed at elevated temperatures offer the following advantages.

This month's Technology Forum looks at the topic of HPLC/Ion Chromatography Focus and the trends and issues surrounding it. Joining us for this discussion is Chris Pohl, VP and Chief Science Officer at Dionex Corporation, Larry Tucker from Metrohm-Peak, and Yuichi Fusho of Shodex.

Chiral Technologies Inc., a provider of chiral chromatography columns, has announced that it will expand Latin American sales efforts by partnering with exclusive distributors.

Waters is acquiring Calorimetry Sciences, a manufacturer of high-performance calorimeters.

In an article recently published in Public Health Nutrition that discusses medicinal herbs? growing popularity, researchers report that While Western medicine currently employs pure, single compounds, CM has long used multiple combinations of compounds in the form of processed natural products, primarily medicinal herbs, to treat and relieve the symptoms of many different human diseases.

In an article recently published in Analytica Chimica Acta, researchers describe the simultaneous determination of sulfamonomethoxine, sulfadimethoxine, and their N4-acetyl metabolites in eggs using restricted-access media high performance liquid chromatography (RAM-HPLC) with a photo-diode array detector.

In an article recently published in the Journal of Nutrition, researchers reported that a mixture of anthocyanins from bilberries and blackcurrants reduced levels of transcription factor NF-kB - responsible for orchestrating a wide range of inflammatory responses.

In an article recently published in Analytica Chimica Acta, researchers developed a procedure for the determination of artemisinin in A. annua using high performance liquid chromatography (HPLC) with evaporative light scattering detection (ELSD) in couple with microwave-assisted extraction (MAE) as an efficient sample preparation technique. Afterwards, method validation system for HPLC?ELSD analysis was developed.

In an article published in Microchemical Journal, researchers used HPLC to determine the linuron preconcentrated on octadecyl silanized (ODS) magnetite.

In this installment of "Column Watch" columnist Ron Majors revisits expert predictions from a survey conducted in 1987. A cross section of column experts of the time were asked a series of questions on the future directions in high performance liquid chromatography (HPLC) column technology. Now, 20 years later, these predictions are contrasted against current column technology. In many cases, the experts were entirely correct, while in other cases, they were dead wrong. Some current trends were not even considered 20 years ago. The author backs up his analysis with current survey information.

Flash chromatography was first introduced by W.C. Still in 1978. The following report published in the June 2006 issue of LCGC North America provided a good overview of the technique.

Faster isn't always better