March 28th 2025
Here is some of the most popular content posted on LCGC International this week.
FDA Talks to LCGC About Chromatographic Techniques for PFAS Detection in Food Supply
December 5th 2023A new study details the US Food and Drug Administration (FDA)’s recent expansion to 30 analytes, from a previous 16, in the method for determining per- and polyfluoroalkyl substances (PFAS) in the US food supply, which, in turn, may mean that additional analytes may still yet be identified (1).
Q&A: FDA Talks to LCGC About Chromatographic Techniques for PFAS Detection in Food Supply
October 13th 2023FDA scientists have expanded the number of analytes in their analytical method for per- and polyfluoroalkyl substances (PFAS), partly in response to updated guidance out of the European Union (EU) on method parameters and limits of quantification (LOQs).
Scientists used supercritical fluid chromatography (SFC) and ultrahigh-pressure liquid chromatography (UHPLC)—both coupled with high-resolution mass spectrometry (HRMS)—to analyze various types of chlorinated paraffins (CPs) in fish oil-based dietary supplements.
Examining Volatile Aromatic Congeners in Irish Whiskey Using GC–MS and GCO
September 20th 2023Professor Kieran N. Kilcawley of Teagasc Food Research Centre and of University College Cork and his colleagues are using gas chromatographic (GC) techniques to explore how to analyze the quality and taste of Irish whiskeys through congener profiles.
Exploring the Potential of Foodomics in the Fight Against Alzheimer’s Disease
August 8th 2023In his keynote lecture at HPLC 2023, Alejandro Cifuentes from the Laboratory of Foodomics, Institute of Food Science Research, CIAL, CSIC in Madrid, Spain, highlighted the promising application of foodomics in addressing Alzheimer’s disease (AD) (1).
LCGC Blog: Forensics Laboratories Underassess Uncertainty in Blood Alcohol Determinations
August 8th 2023The level of uncertainty provided by most forensic laboratories for reported blood alcohol results has been woefully underassessed. Not only is this bad science, but someone’s civil liberties may be at stake.
A Modern Mineral Oil Hydrocarbon Analysis
August 1st 2023Giorgia Purcaro of the University of Liège discusses the advantages offered by the liquid chromatography–comprehensive multidimensional gas chromatography time-of-flight mass spectrometer/flame ionization detector (LC–GCxGC–TOF-MS/FID) method in the analysis of mineral oil.
New Method Enables Accurate Analysis of Aminoglycoside Antibiotic Residues in Aquatic Products
June 30th 2023Researchers have developed an ultrahigh-pressure liquid chromatography (UHPLC)—tandem mass spectrometry (MS/MS) method for the simultaneous determination of 10 aminoglycoside antibiotics in aquatic products.