Application Notes

The UHPLC analysis of four cyclic peptides is shown. Based on the hydrophobicity of the peptides, a YMC-Triart Bio C4 UHPLC column was chosen for this application.

The analysis of FMOC-derivatized glyphosate and AMPA in water samples was performed using a YMC-Triart C18 UHPLC column at an elevated pH of 9.5.

Methods migration from updating analytical equipment can be a time consuming task. This paper shows many examples of method compatibility and analytical equivalency.

LC–MS workflow for accurate quantification/detection of individual host cell proteins, from sample preparation to the reporting of values of process-related impurities.

Efficient and accurate HPLC analysis of lamotrigine in compliance with USP

USP-compliant assay analysis of hydrocortisone using a PerkinElmer LC 300 HPLC System

Efficient and compliant HPLC analysis of pregabalin

Determination of four complex carbohydrates utilizing a PerkinElmer LC 300 HPLC System, a hydrophilic interaction chromatography (HILIC) technique

HPLC method for saccharide content determination via method CRA SACCH.03 through the analysis of nine commercially available high fructose corn syrups

A review of considerations when optimizing high-throughput methods and achieving fast analyses on Avantor® ACE® HTP-MS columns with examples of key LC–MS separations.

Determination of 16 common cannabinoids utilizing a PerkinElmer LC 300 HPLC System

A robust and sensitive HPLC method with multi-wavelength UV–vis detector for the analysis of 2-phenoxyethanol and seven parabens in commercially available PCPs

USP-compliant method for determination of six isoflavone compounds in dietary supplement capsules with the PerkinElmer LC 300 UHPLC System with PDA detector

A rapid and simple LC method for the analysis of six common VOC metabolites in urine for monitoring occupational exposure to VOCs

This application notes introduces an SPE LC–MS/MS methodology using the Microlute™ CP SCX SPE 96-well microplate for the determination of 12 opioids from human urine.

LPGC–MS is a technique that uses the MS vacuum system, along with a specially designed column setup, to lower pressure inside the entire column, speeding up analysis.

This application note describes how human milk oligosaccharides (HMO) can be analyzed by HPTLC during different production steps (fermentation and finished products).

This application note outlines the fractionation of hydrocarbons into aliphatic and aromatic fractions using UCT’s new silver-phase EPH fractionation cartridges.

We show the separation of tacrolimus from its related substances following Ph. Eur. monograph 2244 using the Luna 3 µm C18(2) and Luna Omega µm.

We report the separation of diazoxide and its related organic impurities using a Kinetex ™2.6 µm biphenyl column according to the USP monograph for diazoxide.

This step-by-step selectivity guide is an overview of the reversed-phase HPLC/UHPLC options available to you, highlighting the differences between the columns.

LC–UV assay and organic impurities for paliperidone drug substance based on USP monograph where a L1 (C18) column with 100 x 4.6 mm, 3 µm dimensions was used

LC–MS/MS method to separate furosemide and its metabolite using three different columns: Kinetex 2.6 µm Biphenyl, Luna Omega 1.6 µm C18, and Luna Omega 1.6 µm Polar C18

Luna Omega 1.6µm, 3µm, and 5µm HPLC/UHPLC columns culminate 20 years of technological prowess, advancements, and innovation.