Application Notes: LC
Analysis of Aroma for Beverage Quality Control
Analysis of Organic Acids in Beer
This application describes the analysis of organic acids in beer by ion-exclusion chromatography and postcolumn pH-buffering conductivity detection.
Oligonucleotide Analysis with FlexFire WP C18 1.6 µm (Sept 2022)
This application note covers high-resolution oligonucleotide analysis using FlexFire’s new Wide Pore (WP) C18 1.6 µm column.
UHPLC Analysis of Monoclonal Antibodies Using YMC-Triart Bio C4
YMC-Triart Bio C4 is used to successfully analyze monoclonal antibodies in reversed-phase mode in this robust application.
UHPLC Separation of 11 Cannabinoids on YMC-Triart C18 ExRS
This application note demonstrates the use of YMC-Triart C18 ExRS for UHPLC potency analysis of 11 common cannabinoid compounds.
The Right HIC Column for Each Separation (Sept 2022)
This application note explores when to use each of YMC’s two HIC columns by comparing retention behaviors of BioPro HIC HT and BioPro HIC BF.
Exosome Characterization in Biological Matrices Using AF4-NTA
FFF combined with NTA can be used in the development of therapeutics for biological samples for the optimization process in clinical trials under in vivo conditions.
Biologically Active Increasing Length Peptides
This brief communication highlights the assessment of Hamilton PRP-3 HPLC column attributes when analyzing biologically active peptides.
Overcoming the Challenges of Liquid Chromatography Method Transfer: A CDMO Perspective
This case study demonstrates how method modernization is less difficult than the common perception, and good practices can be put in place to streamline the process.
Isoflavones and Mycotoxins in Soy Beans (August 2022)
Analyzing crops for beneficial and harmful compounds is an indispensable tool for assessing the viability of various agricultural crops for consumption.
Oligonucleotide Analysis with FlexFire WP C18 1.6 µm
This application note covers oligonucleotide analysis using FlexFire’s new Wide Pore (WP) C18 1.6 µm column.
Poisoned by Plastic, Analysis of BPA (July 2022)
Plasticizers added to water bottles to add stability to the bottles can be unknowingly extracted in drinks leading to possible endocrine interactions.
Analysis of Catechins in Tea
This application note demonstrates the performance of the miniLC LC–UV analyzer for the analysis of catechins and epicatechins in teas.
Centrifugal Partition Chromatography (CPC) for Flavouring Industries
This app note shows how CPC can produce a high-quality standard of [6]-gingerol without the use of silica-based chromatography methods, such as FLASH and prep HPLC.
Application Note : VOC Metabolites in Urine by HPLC with UV Detection
A rapid and simple LC method for the analysis of six common VOC metabolites in urine for monitoring occupational exposure to VOCs.
UHPLC Columns for Nucleic Acid Oligomer Analysis
We examined FlexFire columns and their analytical conditions using the synthesized miRNA samples. For this study, we applied inert UHPLC columns to prevent sample loss.
Monoclonal Antibody Analysis
This application details how the FlexFire mAb-RP column allows for accurate analysis of a wide range of molecular sizes.
Characterization of Retroviral Vectors
Large viral vectors are characterized rapidly using dynamic light scattering and in-depth by multi-angle light scattering in combination with field-flow fractionation.
Thermo Scientific Vanquish HPLC and UHPLC Systems Bibliography
This bibliography is a guide to the scope of Vanquish HPLC and UHPLC usage in literature. Publications have been categorized based on either target analyte or field of application.
Successful and stress-free LC method transfers
This compendium features proven techniques to help tackle common instrument challenges faced during method transfers to obtain consistent results and sustain regulatory compliance.
Simultaneous Analysis of Triazole Fungicides by HPLC-DAD
Cannabis Potency Analysis by HPLC
This application note demonstrates the performance of the SCION LC6000 HPLC for the analysis of cannabis potency.
Sensitive Simultaneous Analysis of Lactose, Allolactose, Lactulose, and Saccharides Contained in Low Lactose Dairy Products Using HPLC with Post-column Fluorescence Derivatization Method
This application note introduces a sensitive simultaneous analysis method for lactose, allolactose, lactulose, and, six other saccharides.
Vitamin E(xtraordinary), Isolation of Tocopherols by PRP-1
The fast identification of tocopherols is important for various applications, including free radical scavenging for human health and food-stuff preservation.
Protein Characterization by IEX-MALS
IEX-MALS overcomes some of the restrictions of SEC-MALS that arise from SEC, while providing absolute molar mass, size, and quality assessment of heterogeneous proteins.
Automated Deformulation of LC–MS and GC–MS Data
Accelerate deconvolution of complex MS samples with software that generates an extensive, unbiased, relevant list of structures and component identifiers for your data.
Automated LC–MS Method Development
This application note demonstrates a streamlined HPLC method scouting workflow for the analysis of esomeprazole and related degradation products.
Application Note: NP/RP Analysis of Phosphoramidites
A YMC-Triart C18 and a YMC-Triart SIL column were used in RP and NP mode, respectively, for the analysis of four different phosphoramidites.
High Sensitivity LC–MS Screening of Cytostatics
The recently introduced 1 mm YMC-Triart C18 UHPLC column was used for the high sensitivity LC–MS screening of six antineoplastic drugs.
NP/RP Analysis of Phosphoramidites