Application Notes: LC

This application note covers oligonucleotide analysis using FlexFire’s new Wide Pore (WP) C18 1.6 µm column.

Plasticizers added to water bottles to add stability to the bottles can be unknowingly extracted in drinks leading to possible endocrine interactions. 

This application note demonstrates the performance of the miniLC LC–UV analyzer for the analysis of catechins and epicatechins in teas.

This app note shows how CPC can produce a high-quality standard of [6]-gingerol without the use of silica-based chromatography methods, such as FLASH and prep HPLC.

A rapid and simple LC method for the analysis of six common VOC metabolites in urine for monitoring occupational exposure to VOCs.

We examined FlexFire columns and their analytical conditions using the synthesized miRNA samples. For this study, we applied inert UHPLC columns to prevent sample loss.

This application details how the FlexFire mAb-RP column allows for accurate analysis of a wide range of molecular sizes.

Large viral vectors are characterized rapidly using dynamic light scattering and in-depth by multi-angle light scattering in combination with field-flow fractionation.

This bibliography is a guide to the scope of Vanquish HPLC and UHPLC usage in literature. Publications have been categorized based on either target analyte or field of application.

This compendium features proven techniques to help tackle common instrument challenges faced during method transfers to obtain consistent results and sustain regulatory compliance.

This application note demonstrates the performance of the SCION LC6000 HPLC for the analysis of cannabis potency.

This application note introduces a sensitive simultaneous analysis method for lactose, allolactose, lactulose, and, six other saccharides.

The fast identification of tocopherols is important for various applications, including free radical scavenging for human health and food-stuff preservation.

IEX-MALS overcomes some of the restrictions of SEC-MALS that arise from SEC, while providing absolute molar mass, size, and quality assessment of heterogeneous proteins.

Accelerate deconvolution of complex MS samples with software that generates an extensive, unbiased, relevant list of structures and component identifiers for your data.

This application note demonstrates a streamlined HPLC method scouting workflow for the analysis of esomeprazole and related degradation products.

A YMC-Triart C18 and a YMC-Triart SIL column were used in RP and NP mode, respectively, for the analysis of four different phosphoramidites.

The recently introduced 1 mm YMC-Triart C18 UHPLC column was used for the high sensitivity LC–MS screening of six antineoplastic drugs.

A YMC-Triart C18 and a YMC-Triart SIL column were used in RP and NP mode, respectively, for the analysis of four different phosphoramidites.

Mipomersen was analyzed by LC–HRMS using a biocompatible YMC-Triart C8 metal-free column, ensuring symmetric peaks, high sensitivity, and no carryover effects.

The separation of three cell-penetrating peptides (CPPs) was performed using a YMC-Triart C18 UHPLC column, providing sharp peaks for a fast analysis in under 4 min.

Twenty-eight PFAS in human serum were analyzed using a YMC-Triart C18 column. An automated SPE system was coupled to an online SPE column-switching LC–MS/MS method.

Four hydrophilic dipeptides were separated with excellent resolution using a YMC-Triart SIL column. Even structurally similar dipeptides were separated in under 4 min.

The UHPLC analysis of four cyclic peptides is shown. Based on the hydrophobicity of the peptides, a YMC-Triart Bio C4 UHPLC column was chosen for this application.

The analysis of FMOC-derivatized glyphosate and AMPA in water samples was performed using a YMC-Triart C18 UHPLC column at an elevated pH of 9.5.

Efficient and accurate HPLC analysis of lamotrigine in compliance with USP

USP-compliant assay analysis of hydrocortisone using a PerkinElmer LC 300 HPLC System

Efficient and compliant HPLC analysis of pregabalin

Determination of four complex carbohydrates utilizing a PerkinElmer LC 300 HPLC System, a hydrophilic interaction chromatography (HILIC) technique