Application Notes: LC

HPLC method for saccharide content determination via method CRA SACCH.03 through the analysis of nine commercially available high fructose corn syrups

Determination of 16 common cannabinoids utilizing a PerkinElmer LC 300 HPLC System

USP-compliant method for determination of six isoflavone compounds in dietary supplement capsules with the PerkinElmer LC 300 UHPLC System with PDA detector

A rapid and simple LC method for the analysis of six common VOC metabolites in urine for monitoring occupational exposure to VOCs

We show the separation of tacrolimus from its related substances following Ph. Eur. monograph 2244 using the Luna 3 µm C18(2) and Luna Omega µm.

We report the separation of diazoxide and its related organic impurities using a Kinetex ™2.6 µm biphenyl column according to the USP monograph for diazoxide.

Easily determine the allowable adjustments that can be made to European Pharmacopoeia (EP) methods and find the right column for your method.

Quickly view allowable adjustments outlined by the United States Pharmacopeia (USP) and select the proper Phenomenex column for your monograph using this simple guide.

Improve United States Pharmacopeia (USP) method performance with allowable adjustments

A robust and sensitive HPLC method with multi-wavelength UV–vis detector for the analysis of 2-phenoxyethanol and seven parabens in commercially available PCPs .

Critical quality attributes of lentivirus vector products can be assessed by centrifugal field-flow fractionation coupled to multi-angle light scattering (CF3-MALS).

Accurate detection of HAAs is paramount for the prevention of over oxidation, while still managing enough water sanitation to eliminate water-borne pathogens.

Chemically resistant resin bed allows for a wide base of mobile-phase choices with excellent anion separation.        

Contamination of drinking water and food sources is of great concern. Isolation and quantification of the various arsenic states are identified.

Isolation of six common allergens by the utilization of reversed-phase HPLC using an alkaline eluent

Chromium can pose as a beneficial element or a poison, therefore it is imperative to identify contaminated waters, especially drinking water.          

The fight against cancer employs many tools. Paclitaxel, a compound found in the bark of the Pacific yew tree, is one that that has been found to make a big difference.

A variety of C18-type columns are evaluated for the identification of levetiracetam via the USP monograph.

Symmetrical, well-resolved peaks easily meet USP performance requirements for the analysis of levetiracetam impurities.

Symmetrical, well-resolved peaks easily meet USP performance requirements for the analysis of pramipexole dihydrochloride.

Easily meet USP method requirements with reduced backpressure using a larger ID column.

A variety of C18-type columns are evaluated for the identification of hydrocortisone via the USP monograph.

Looking to switch LC columns for pharmaceutical drug applications? Method transfer from Luna columns is made seamless with the targeted selectivity of Sonoma LC columns.

A quick reference chart explaining allowable changes to isocratic and gradient HPLC methods

Symmetrical, well-resolved peaks easily meet USP performance requirements for the analysis of fluconazole.

Plasticizers added to water bottles to add stability to the bottles can be unknowingly extracted in drinks leading to possible endocrine interactions. 

In this application note, an HPLC with MWD detection method is detailed to detect parabens in cosmetic and personal care products.

A simple, fast, robust green chemistry method for the accurate quantitation of six additives in diet soft drinks using HPLC with photodiode array (PDA) detection.

Purification of peptide-peptoid hybrids can be obtained by reversed-phase chromatography with excellent recovery and resolution.

The ability to collect compounds is related to the ability to detect them. Many possess weak or non-existent chromophores, causing UV detection to exhibit poor yields.