Application Notes: LC
Application Note: Erythromycin Ointments According US Pharmacopeia
Erythromycin analysis in creams, lotions, etc., based on HPAEC-PAD using the ALEXYS Antibiotics Analyzer according to the official 2018 USP 41—NF36 monograph.
Sulfamethoxazole (SMX) and Trimethoprim (TMP) Antibiotic Analysis
SMX and TMP are the active ingredients of Co-trimoxazole or Bactrim. They can be analyzed easily and inexpensively using HPLC with pulsed amperometric detection.
Amikacin and Kanamycin According US Pharmacopeia
The ALEXYS HPAEC-PAD Analyzer is used for the analysis of both antibiotics, in accordance with the USP 38 monographs.
Application Note: Carbohydrates in Plant Ecology
A HPAEC-PAD method is presented for the sensitive analysis of mono-, di-, and trisaccharides in plant tissue extracts and root exudates..
Lactose Detection in Lactose-free Labelled Dairy Products
This application note demonstrates a fast, selective, and sensitive method for the analysis of lactose and isomers based on HPAEC with Pulsed Amperometric Detection.
Analysis of Sugar Alcohols used as Sweeteners
A HPAEC-PAD method with a four-step potential waveform is applied for the analysis of Erythritol, Xylitol, Sorbitol, Mannitol, and Maltitol, resulting in excellent reproducibility.
Application Note: Azithromycin According US Pharmacopeia
The ALEXYS Antibiotics Analyzer is used for routine assay and impurity analysis of Azithromycin in various formulations according USP 41 monographs.
Application Note: Poisoned by Plastic, Analysis of BPA
Plasticizers added to water bottles to add stability to the bottles can be unknowingly extracted in drinks leading to possible endocrine interactions.
Comprehensive Fractionation of Herbal Medicine Components
This article introduces a comprehensive fractionation for both UV absorbing and non-UV absorbing compounds using a newly designed PDA-ELSD triggered preparative LC.
Poisoned by Plastic, Analysis of BPA
HPLC Analysis of Finasteride Using an Epic C18 HPLC Column
The Epic C18 column provides efficient and repeatable separations for finasteride, meeting all suitability requirements in the USP monograph.
HPLC Analysis of Betamethasone Dipropionate Using Epic C18 HPLC Column
The superior base deactivation and high-density bonding technology of the Epic C18 phase yields excellent peak shape in betamethasone analyses.
HPLC Analysis of Acetaminophen, Aspirin, and Caffeine Using an Epic C18 Column in Accordance with the USP
This application brief describes the use of an Epic C18 column for the analysis of acetaminophen, aspirin, and caffeine yielding rapid and reproducible results.
HPLC Analysis of Common Ginsenosides Found in Ginseng Using the Chinese Pharmacopeia
This application brief describes the use of an EpicTM C18 to analyze three ginsenosides using a method based on the Chinese Pharmacopeia.
Purification of Peptides and Proteins
Learn how to use flash chromatography and prep HPLC for protein purification, parameters that improve resolution, and how to select the stationary phase and solvent.
Determination of PAH4 in Edible Oils with Automated Sample Preparation
This note demonstrates the determination of PAH4 inedible oils with automated sample enrichment and matrix elimination (online solid-phase extraction - online SPE).
Dual Injection (U)HPLC for Analysis of Pharmaceuticals
This application demonstrates the efficiency, throughput, and reliability of a dual-injection system for finished pharmaceutical products and in-process APIs.
Single-Step Purification of Minor Cannabinoids by CPC
Cannabinoids have similar molecular structures, making purification a challenging step. Learn how centrifugal partition chromatography can simplify this process.
App Note: A Rainbow of Synthesized Color
Synthetically derived food and beverage dye analysis to meet regulatory requirements aimed at reducing the risk of allergies, cancers, and attention deficits.
Pharmaceutical Quality Control: The Reference Standards Labyrinth (NA)
Hexavalent Chromium Determination Hamilton PRP-X100 Anion Exchange HPLC Column v2
Arsenic Speciation on Hamilton PRP-X100 v2
Separation of Halo Acetic Acids by Ion Exclusion
Flexible Anion Analysis with Hamilton PRP-X100 and X110 Columns v2
Separation of Aflatoxins on HxSil C18 v2
Promoter or Polluter? Separation of Triazines on HxSil C18 Column v2
Pharmaceutical Quality Control: The Reference Standards Labyrinth
Garlic, Panacea or Placebo
Sulfide compounds found in garlic oils are used in therapeutics and prophylaxis of certain cancers and are prevalent in cell health.
Legumes – Blessing and Curse?
Identification and quantification of the raffinose family of oligosaccharides allows a more thorough understanding of an individual’s gut health.
Rapid Analysis of Plasmid Topoisomers
AEX using a TSKgel® DNA-NPR column offers a rapid method for discriminating between covalently closed circular, open circular, and linear forms of plasmid DNA.