Application Notes: LC

In this application note, we profile capsid protein peptides from AAV5 and AAV9, digested with trypsin using a Biozen™ Peptide XB-C18 reversed phase column.

We present an LC-HRMS approach to distinguishing a pool of multiple caps and their relative integrity of digested mRNA oligonucleotide strands of 1250 nucleotides.

Review profiling of denatured and dissociated capsid proteins from AAV5 and AAV9, via analysis with LC-MS using a Biozen™ Intact XB-C8 reversed phase column.

We present electrical asymmetrical flow field-flow fractionation with multi-angle light scattering (EAF4-MALS) to derive parameters of a liposomal form of doxorubicin.

A separation of antidepressants is compared between a fully porous C18 and the HALO® PCS C18 column.

A synthetic peptide panel is screened on the HALO® Peptide PCS C18 and compared to a standard peptide C18 stationary phase.

Built upon Fused-Core® technology, the HALO® PCS C18 maintains peak symmetry at high loading capacities and provides alternate selectivity for C18 bonded phases.

The new HALO® PCS C18 phase offers an alternative to chromatographic separations.

In a head-to-head SPP comparison of two positively charged C18 surface chemistries, the HALO 90 Å PCS C18 obtains improved resolution, efficiency, and tailing factors.

In this study, a generic, 5-min linear gradient was used to separate six basic drug compounds on a short (50 mm) PRP-C18 column.

Identification of polyphenolic catechin compounds for health and industrial quantification and quality control of tea products.

Nine structurally diverse, strongly basic drug compounds are resolved in less than 2 minutes using a high pH mobile phase and a fast acetonitrile gradient at 80 °C.

The diterpenoid, paclitaxel, is as a potent chemotherapy agent for breast and ovarian cancer. Here, the isolation of paclitaxel from its major impurities is shown.

Chemically resistant resin bed allows for a wide base of mobile phase choices with excellent anion separation

Identifying benzodiazepine metabolites can be highly valuable in detecting abuse. Metabolites of oxazepam are found containing both hydroxyl and glucuronides.

A reversed-phase HPLC method was developed to separate five steroid hormones, with partition coefficients ranging from 1.47 (cortisone) to 4.5 (pregnenolone).

Complementarity in chromatography ensures accurate purity. Daicel offers non-chiral stationary phases compatible in different modes for cyclic peptide analysis.

This tech note describes a method of continuous monitoring of flow rate to provide real-time validation of the LC system performance, improving reliability of results.

Complementarity in chromatography ensures accurate purity. Daicel offers non-chiral stationary phases compatible in different modes for cyclic peptide analysis.

Accurate purity assessment of oligonucleotide mixtures can be challenging due to their complexity. Daicel offers several solutions that provide unique selectivity.

Complementarity in chromatography ensures accurate purity. Daicel offers non-chiral stationary phases compatible in different modes for cyclic peptide analysis.

Despite the utility of the essential oil mixture, it has been shown that allergies can arise from some of the individual components.

Nine structurally diverse, strongly basic drug compounds are resolved in less than 2 minutes using a high pH mobile phase and a fast acetonitrile gradient.

Chemically resistant resin bed allows for a wide base of mobile phase choices with excellent anion separation

This focuses on the identification of polyphenolic catechin compounds for health and industrial quantification and quality control of tea products.

The isolation of the diterpenoid, paclitaxel, from its major impurities is shown with the use of Hamilton’s PRP-1 (5 µm) HPLC column.

A reversed-phase HPLC method was developed for separation of five steroid hormones with partition coefficients ranging from 1.47 (cortisone) to 4.5 (pregnenolone).