Wednesday Morning Session Preview
The June 18 Wednesday morning session "The Triple Quadrupole: 35 Years of Evolution and Application to Celebrate Chris Enke's 80th Birthday" starts at 8:30 a.m. in Room 309-301. R. Graham Cooks, of Purdue University (West Lafayette, Indiana), will preside.
Room 309-310
The June 18 Wednesday morning session “The Triple Quadrupole: 35 Years of Evolution and Application to Celebrate Chris Enke’s 80th Birthday” starts at 8:30 a.m. in Room 309-301. R. Graham Cooks, of Purdue University (West Lafayette, Indiana), will preside.
Richard A. Yost, of the University of Florida (Gainesville, Florida) will give the first presentation at 8:30 a.m., titled “The Triple Quadrupole: An Historical Perspective.”
At 8:50 a.m., David P.A. Kilgour, of the School of Pharmacy, University of Maryland (Baltimore, Maryland) will present “The Secret Identity of Phase-Space ‘Ellipses’ – Are They Misnamed?”
Following Kilgour, Mircea Guna, of AB Sciex (Concord, Canada) will give talk at 9:10 a.m. titled “Mass Selective Axial Ejection in a Low Pressure Linear Ion Trap in the Presence of Nonlinear RF Fields.”
The next speaker, starting at 9:30 a.m., will be Alan Schoen, of Thermo Fisher Scientific (San Jose, California). Schoen will give a presentation titled “Moore’s Law and the Consequence of Technological Change.”
Sarfaraz Syed, of FOM Institute AMOLF (Amsterdam, The Netherlands), will follow Schoen’s presentation with a talk starting at 9:50 a.m. titled “Performance Investigation and Mass Resolution Enhancement of an Electrospray Ionization Quadrupole Mass Spectrometer with a Position Sensitive Detector.”
The session will close with a final presentation at 10:10 a.m. by Christie G. Enke, of the University of New Mexico (Placitas, New Mexico) titled “Room for Improvement.”
AI and GenAI Applications to Help Optimize Purification and Yield of Antibodies From Plasma
October 31st 2024Deriving antibodies from plasma products involves several steps, typically starting from the collection of plasma and ending with the purification of the desired antibodies. These are: plasma collection; plasma pooling; fractionation; antibody purification; concentration and formulation; quality control; and packaging and storage. This process results in a purified antibody product that can be used for therapeutic purposes, diagnostic tests, or research. Each step is critical to ensure the safety, efficacy, and quality of the final product. Applications of AI/GenAI in many of these steps can significantly help in the optimization of purification and yield of the desired antibodies. Some specific use-cases are: selecting and optimizing plasma units for optimized plasma pooling; GenAI solution for enterprise search on internal knowledge portal; analysing and optimizing production batch profitability, inventory, yields; monitoring production batch key performance indicators for outlier identification; monitoring production equipment to predict maintenance events; and reducing quality control laboratory testing turnaround time.
