TLC Product Showcase
TLC Product Showcase
Pre-scraped rotors
Available from Analtech are pre-scraped rotors that are sandwiched between specially molded plastic trays. These rotors can be taken directly from the packaging to the company's CycloGraph or Chromatotron system and be used immediately. All sizes from 1 mm to 8 mm are available. Additionally, the packaging can be used as a storage rack.
Analtech Inc., Newark, Delaware, USA.
TLC brochure and plates
Merck offers a brochure covering its complete range of thin layer chromatography (TLC) products. Product families consist of a broad range of conventional silica TLC plates, high performance silica plates (HPTLC) and a wide choice of RP-modified and cellulose plates. Additionally, various special products are included in the brochure such as concentrating zone plates and the company's UTLC and LiChrospher. In addition to this brochure offer, the company has released two types of HPTLC plates. The ProteoChrom silica and the ProteoChrom cellulose are both suitable for peptide analysis. The 20 × 20 cm PoteoChrom silica plates use an extra thin 100 μm silica layer that is suitable for one-dimensional separations. Whereas the 10 × 10 cm ProteoChrom cellulose sheets are optimal for two-dimensional separations. Both of these plates include special developed user protocols that cover all steps from plate development to detection with recommendations on solvent systems and staining.
Merck KgaA, Darmstadt, Germany.
Bibliography service for TLC
Camag has released a bibliography service that includes more than 100 abstracts of recent publications, demonstrating the flexibility of thin-layer chromatography (TLC). The CBS 98 emphasises planar chromatography as an essential component of modern analysis, for example, a method for the identification of unknown toxins in water using high performance (HP)TLC–MS coupling is featured. This bibliography is free-of-charge and an updated cumulative version can be downloaded from the company's website. Additionally, Camag Laboratory, the centre for applied HPTLC now has its own website: www.camag-laboratory.com. Results of basic and applied research projects are available through the website and a portfolio of services has been established to share knowledge with customers.
CAMAG, Muttenz, Switzerland.
TLC plates with a highly reflective surface
Available from Thomas Scientific are Whatman Diamond TLC plates that feature a highly reflective surface to minimize background noise while scanning for maximum range in detection. These plates feature an organic binder for the prevention of surface deterioration and are claimed to reduce band spreading because of uniform particle size and distribution. Additionally, the silica gel plates are available with channelling and linear preadsorbent spotting area and they have UV-254 fluorescent indicator.
Thomas Scientific, Swedesboro, New Jersey, USA.
Hard-layer TLC plate
Macherey-Nagel has introduced a hard layer thin-layer chromatography (TLC)-plate with unmodified silica. Adamant plates feature an organic binder system that results in a hard silica layer. It is claimed that as a result of the high abrasion resistance, the formation of dust on the surface of these plates is minimized. Although the abrasion resistance prevents undesired changes or damage to the layer (thickness) during transportation and/or handling the plates can be easily marked with a pencil for identification. A dust-free plate allows convenient handling and avoids silica contamination of the TLC developing chamber. Reportedly, the UV indicator of these TLC plates features an increased brilliance that, in combination with the low-noise background, results in an increased detection sensitivity.
Macherey-Nagel GmbH & Co. KG, Düren, Germany.
2024 EAS Awardees Showcase Innovative Research in Analytical Science
November 20th 2024Scientists from the Massachusetts Institute of Technology, the University of Washington, and other leading institutions took the stage at the Eastern Analytical Symposium to accept awards and share insights into their research.
Inside the Laboratory: The Richardson Group at the University of South Carolina
November 20th 2024In this edition of “Inside the Laboratory,” Susan Richardson of the University of South Carolina discusses her laboratory’s work with using electron ionization and chemical ionization with gas chromatography–mass spectrometry (GC–MS) to detect DBPs in complex environmental matrices, and how her work advances environmental analysis.
AI and GenAI Applications to Help Optimize Purification and Yield of Antibodies From Plasma
October 31st 2024Deriving antibodies from plasma products involves several steps, typically starting from the collection of plasma and ending with the purification of the desired antibodies. These are: plasma collection; plasma pooling; fractionation; antibody purification; concentration and formulation; quality control; and packaging and storage. This process results in a purified antibody product that can be used for therapeutic purposes, diagnostic tests, or research. Each step is critical to ensure the safety, efficacy, and quality of the final product. Applications of AI/GenAI in many of these steps can significantly help in the optimization of purification and yield of the desired antibodies. Some specific use-cases are: selecting and optimizing plasma units for optimized plasma pooling; GenAI solution for enterprise search on internal knowledge portal; analysing and optimizing production batch profitability, inventory, yields; monitoring production batch key performance indicators for outlier identification; monitoring production equipment to predict maintenance events; and reducing quality control laboratory testing turnaround time.
Infographic: Be confidently audit ready, at any time and reduce failures in pharma QC testing
November 20th 2024Discover how you can simplify the audit preparation process with data integrity dashboards that provide transparency to key actions, and seamlessly track long-term trends and patterns, helping to prevent system suitability failures before they occur with waters_connect Data Intelligence software.
Critical Role of Oligonucleotides in Drug Development Highlighted at EAS Session
November 19th 2024A Monday session at the Eastern Analytical Symposium, sponsored by the Chinese American Chromatography Association, explored key challenges and solutions for achieving more sensitive oligonucleotide analysis.
