TLC Product Showcase
TLC Product Showcase
Pre-scraped rotors
Available from Analtech are pre-scraped rotors that are sandwiched between specially molded plastic trays. These rotors can be taken directly from the packaging to the company's CycloGraph or Chromatotron system and be used immediately. All sizes from 1 mm to 8 mm are available. Additionally, the packaging can be used as a storage rack.
Analtech Inc., Newark, Delaware, USA.
TLC brochure and plates
Merck offers a brochure covering its complete range of thin layer chromatography (TLC) products. Product families consist of a broad range of conventional silica TLC plates, high performance silica plates (HPTLC) and a wide choice of RP-modified and cellulose plates. Additionally, various special products are included in the brochure such as concentrating zone plates and the company's UTLC and LiChrospher. In addition to this brochure offer, the company has released two types of HPTLC plates. The ProteoChrom silica and the ProteoChrom cellulose are both suitable for peptide analysis. The 20 × 20 cm PoteoChrom silica plates use an extra thin 100 μm silica layer that is suitable for one-dimensional separations. Whereas the 10 × 10 cm ProteoChrom cellulose sheets are optimal for two-dimensional separations. Both of these plates include special developed user protocols that cover all steps from plate development to detection with recommendations on solvent systems and staining.
Merck KgaA, Darmstadt, Germany.
Bibliography service for TLC
Camag has released a bibliography service that includes more than 100 abstracts of recent publications, demonstrating the flexibility of thin-layer chromatography (TLC). The CBS 98 emphasises planar chromatography as an essential component of modern analysis, for example, a method for the identification of unknown toxins in water using high performance (HP)TLC–MS coupling is featured. This bibliography is free-of-charge and an updated cumulative version can be downloaded from the company's website. Additionally, Camag Laboratory, the centre for applied HPTLC now has its own website: www.camag-laboratory.com. Results of basic and applied research projects are available through the website and a portfolio of services has been established to share knowledge with customers.
CAMAG, Muttenz, Switzerland.
TLC plates with a highly reflective surface
Available from Thomas Scientific are Whatman Diamond TLC plates that feature a highly reflective surface to minimize background noise while scanning for maximum range in detection. These plates feature an organic binder for the prevention of surface deterioration and are claimed to reduce band spreading because of uniform particle size and distribution. Additionally, the silica gel plates are available with channelling and linear preadsorbent spotting area and they have UV-254 fluorescent indicator.
Thomas Scientific, Swedesboro, New Jersey, USA.
Hard-layer TLC plate
Macherey-Nagel has introduced a hard layer thin-layer chromatography (TLC)-plate with unmodified silica. Adamant plates feature an organic binder system that results in a hard silica layer. It is claimed that as a result of the high abrasion resistance, the formation of dust on the surface of these plates is minimized. Although the abrasion resistance prevents undesired changes or damage to the layer (thickness) during transportation and/or handling the plates can be easily marked with a pencil for identification. A dust-free plate allows convenient handling and avoids silica contamination of the TLC developing chamber. Reportedly, the UV indicator of these TLC plates features an increased brilliance that, in combination with the low-noise background, results in an increased detection sensitivity.
Macherey-Nagel GmbH & Co. KG, Düren, Germany.
New Study Uses MSPE with GC–MS to Analyze PFCAs in Water
January 20th 2025Scientists from the China University of Sciences combined magnetic solid-phase extraction (MSPE) with gas chromatography–mass spectrometry (GC–MS) to analyze perfluoro carboxylic acids (PFCAs) in different water environments.
The Next Frontier for Mass Spectrometry: Maximizing Ion Utilization
January 20th 2025In this podcast, Daniel DeBord, CTO of MOBILion Systems, describes a new high resolution mass spectrometry approach that promises to increase speed and sensitivity in omics applications. MOBILion recently introduced the PAMAF mode of operation, which stands for parallel accumulation with mobility aligned fragmentation. It substantially increases the fraction of ion used for mass spectrometry analysis by replacing the functionality of the quadrupole with high resolution ion mobility. Listen to learn more about this exciting new development.
A Guide To Finding the Ideal Syringe and Needle
January 20th 2025Hamilton has produced a series of reference guides to assist science professionals in finding the best-suited products and configurations for their applications. The Syringe and Needle Reference Guide provides detailed information on Hamilton Company’s full portfolio of syringes and needles. Everything from cleaning and preventative maintenance to individual part numbers are available for review. It also includes selection charts to help you choose between syringe terminations like cemented needles and luer tips.
The Complexity of Oligonucleotide Separations
January 9th 2025Peter Pellegrinelli, Applications Specialist at Advanced Materials Technology (AMT) explains the complexity of oligonucleotide separations due to the unique chemical properties of these molecules. Issues such as varying length, sequence complexity, and hydrophilic-hydrophobic characteristics make efficient separations difficult. Separation scientists are addressing these challenges by modifying mobile phase compositions, using varying ion-pairing reagents, and exploring alternative separation modes like HILIC and ion-exchange chromatography. Due to these complexities, AMT has introduced the HALO® OLIGO column, which offers high-resolution, fast separations through its innovative Fused-Core® technology and high pH stability. Alongside explaining the new column, Peter looks to the future of these separations and what is next to come.
Oasis or Sand Dune? Isolation of Psychedelic Compounds
January 20th 2025Magic mushrooms, once taboo, have recently experienced a renaissance. This new awakening is partially due to new findings that indicate the effects of psilocybin, and its dephosphorylated cousin psilocin may produce long lasting results for patients who might be struggling with anxiety, depression, alcohol and drug abuse, and post-traumatic stress disorder. Hamilton Company has developed a methodology for the isolation and identification of 5 common psychedelic compounds used in the potential treatment of disease. The PRP-1 HPLC column resin remains stable in the harsh alkaline conditions ideal for better separations.
