SEC Analysis of Star Branched Polyethylene Glycol without Column Interaction
Recent advances in polymer chemistry have led to the development of novel materials with both controlled functionality and structure resulting in unusual rheological properties. Examples include the many di- and triblock copolymer architectures and dendritic systems. These materials often include regions of different polarity and hydrophobicity and therefore represent a challenge to the analytical chemist. This application note illustrates the analysis of a star-branched polyethylene glycol with a significant hydrophobic component by aqueous SEC.
LCGC’s Year in Review: Highlights in Liquid Chromatography
December 20th 2024This collection of technical articles, interviews, and news pieces delves into the latest innovations in LC methods, including advance in high performance liquid chromatography (HPLC), ultrahigh-pressure liquid chromatography (UHPLC), liquid chromatography–mass spectrometry (LC–MS), and multidimensional LC.
Using LC-MS/MS to Measure Testosterone in Dried Blood Spots
December 19th 2024Testosterone measurements are typically performed using serum or plasma, but this presents several logistical challenges, especially for sample collection, storage, and transport. In a recently published article, Yehudah Gruenstein of the University of Miami explored key insights gained from dried blood spot assay validation for testosterone measurement.
