Researchers Discover Intravenous Immune Globulin Improves Quality of Life in Patients With Chronic Inflammatory Demyelinating Polyneuropathy
Researcher Ingemar S. J. Merkies, MD, (Rotterdam, The Netherlands) and colleagues discovered that patients with chronic inflammatory demyelinating polyneuropathy (CIDP) benefit from treatment with immune globulin intravenous 10% caprylate/chromatography purified (IGIV-C).
Researcher Ingemar S. J. Merkies, MD, (Rotterdam, The Netherlands) and colleagues discovered that patients with chronic inflammatory demyelinating polyneuropathy (CIDP) benefit from treatment with immune globulin intravenous 10% caprylate/chromatography purified (IGIV-C). The study consisted of 117 patients, aged 18 years or older, with CIDP and progressive or relapsing motor and sensory dysfunction of at least 1 limb and clinical disability ranging from 2 to 9 on the Inflammatory Neuropathy Cause and Treatment (INCAT) disability scale. Results of the study, presented on September 22 at the American Neurological Association 133rd Annual Meeting , show that patients treated with IGIV-C had a greater improvement on the physical component score of the Short Form-36 Quality of Life Scale (SF-36) compared with those treated with placebo (P = .020).
Modern HPLC Strategies: Improving Retention and Peak Shape for Basic Analytes
August 16th 2024In high-performance liquid chromatography (HPLC), it is common for bases and unreacted ionized silanols on silica-based columns to cause irreproducible retention, broad peaks, and peak tailing when working with basic analytes. David S. Bell, Lead Consultant at ASKkPrime LLC offers innovative HPLC strategies that can help mitigate such issues.
Characterizing Cooked Cheese Flavor with Gas Chromatography
September 19th 2024A joint study by the Department of Food and Nutritional Sciences at the University of Reading and Synergy Flavours aimed to identify volatiles that contribute to the aroma of cooked cheese, including the role of fat content in development during cooking.
