Researcher Ingemar S. J. Merkies, MD, (Rotterdam, The Netherlands) and colleagues discovered that patients with chronic inflammatory demyelinating polyneuropathy (CIDP) benefit from treatment with immune globulin intravenous 10% caprylate/chromatography purified (IGIV-C).
Researcher Ingemar S. J. Merkies, MD, (Rotterdam, The Netherlands) and colleagues discovered that patients with chronic inflammatory demyelinating polyneuropathy (CIDP) benefit from treatment with immune globulin intravenous 10% caprylate/chromatography purified (IGIV-C). The study consisted of 117 patients, aged 18 years or older, with CIDP and progressive or relapsing motor and sensory dysfunction of at least 1 limb and clinical disability ranging from 2 to 9 on the Inflammatory Neuropathy Cause and Treatment (INCAT) disability scale. Results of the study, presented on September 22 at the American Neurological Association 133rd Annual Meeting , show that patients treated with IGIV-C had a greater improvement on the physical component score of the Short Form-36 Quality of Life Scale (SF-36) compared with those treated with placebo (P = .020).
LCGC’s Year in Review: Highlights in Liquid Chromatography
December 20th 2024This collection of technical articles, interviews, and news pieces delves into the latest innovations in LC methods, including advance in high performance liquid chromatography (HPLC), ultrahigh-pressure liquid chromatography (UHPLC), liquid chromatography–mass spectrometry (LC–MS), and multidimensional LC.
Using LC-MS/MS to Measure Testosterone in Dried Blood Spots
December 19th 2024Testosterone measurements are typically performed using serum or plasma, but this presents several logistical challenges, especially for sample collection, storage, and transport. In a recently published article, Yehudah Gruenstein of the University of Miami explored key insights gained from dried blood spot assay validation for testosterone measurement.