Researchers Analyze Complex Sugar Molecule Using LC-MS
A Team of Scientists from MIT have developed a method for unveiling the genetic code of heparan sulfate (a sugar molecule found on the surface of all cells in the body) and heparin (a commercial drug used to stop clotting).
A Team of Scientists from MIT have developed a method for unveiling the genetic code of heparan sulfate (a sugar molecule found on the surface of all cells in the body) and heparin (a commercial drug used to stop clotting).
For years, researchers have been able to determine the genetic codes of protein and DNA, however, doing the same for sugars has proven to be troublesome because of the complexity of these molecules.
Led byMIT Professor of Biology Robert D. Rosenberg and postdoctoral associates Kuberan Balagurunathan and Zhengliang L. Wu, technical associate Miroslaw Lech, research affiliate Lijuan Zhang, and research scientist David Beeler, the technique developed by the group uses LC-MS.
To view, please visit: http://web.mit.edu/newsoffice/nr/2002/sugar2.html
LCGC’s Year in Review: Highlights in Liquid Chromatography
December 20th 2024This collection of technical articles, interviews, and news pieces delves into the latest innovations in LC methods, including advance in high performance liquid chromatography (HPLC), ultrahigh-pressure liquid chromatography (UHPLC), liquid chromatography–mass spectrometry (LC–MS), and multidimensional LC.
Using LC-MS/MS to Measure Testosterone in Dried Blood Spots
December 19th 2024Testosterone measurements are typically performed using serum or plasma, but this presents several logistical challenges, especially for sample collection, storage, and transport. In a recently published article, Yehudah Gruenstein of the University of Miami explored key insights gained from dried blood spot assay validation for testosterone measurement.
