Optimizing Separations Using Coupled Columns and Window Diagramming
In this month's "GC Connections," guest columnist Dean Rood writes about optimizing separations using combinations of two columns connected in a series. These coupled column systems produce peak separations that are a combination of separations achieved on each column individually. He describes the geographical window diagramming approach to determining the optimal combination of column lengths for several separations and column combinations and compares the results with those obtained using mixed stationary-phase chemistry.
LCGC 17(10), 914–922 (1999)
New Study Reviews Chromatography Methods for Flavonoid Analysis
April 21st 2025Flavonoids are widely used metabolites that carry out various functions in different industries, such as food and cosmetics. Detecting, separating, and quantifying them in fruit species can be a complicated process.
University of Rouen-Normandy Scientists Explore Eco-Friendly Sampling Approach for GC-HRMS
April 17th 2025Root exudates—substances secreted by living plant roots—are challenging to sample, as they are typically extracted using artificial devices and can vary widely in both quantity and composition across plant species.
Sorbonne Researchers Develop Miniaturized GC Detector for VOC Analysis
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