Optimizing Separations Using Coupled Columns and Window Diagramming
In this month's "GC Connections," guest columnist Dean Rood writes about optimizing separations using combinations of two columns connected in a series. These coupled column systems produce peak separations that are a combination of separations achieved on each column individually. He describes the geographical window diagramming approach to determining the optimal combination of column lengths for several separations and column combinations and compares the results with those obtained using mixed stationary-phase chemistry.
LCGC 17(10), 914–922 (1999)
Study Examines Impact of Zwitterionic Liquid Structures on Volatile Carboxylic Acid Separation in GC
March 28th 2025Iowa State University researchers evaluated imidazolium-based ZILs with sulfonate and triflimide anions to understand the influence of ZILs’ chemical structures on polar analyte separation.
Quantifying Microplastics in Meconium Samples Using Pyrolysis–GC-MS
March 26th 2025Using pyrolysis-gas chromatography and mass spectrometry, scientists from Fudan University and the Putuo District Center for Disease Control and Prevention detected and quantified microplastics in newborn stool samples.
