Superheated Water: A New Look at Chromatographic Eluents for Reversed-Phase HPLC
The authors propose using water superheated to 100–240 ºC as an alternative liquid eluent for reversed-phase high performance liquid chromatography (HPLC) to overcome many of the problems of toxicity, flammability, and cost associated with organic modifiers. Superheated water has been demonstrated as an eluent with a number of stationary phase materials, including poly(styrene-divinylbenzene) and porous graphitic carbon both isothermally and in thermal gradient mode. It is compatible with conventional HPLC spectroscopic detectors and also can be used with flame ionization, nuclear magnetic resonance spectroscopy, and mass spectrometry detectors. The authors provide examples of separation applications, including aromatic compounds, pharmaceutical compounds, and vitamins.
LCGC 17(10), 938–945 (1999)
RAFA 2024 Highlights: Contemporary Food Contamination Analysis Using Chromatography
November 18th 2024A series of lectures focusing on emerging analytical techniques used to analyse food contamination took place on Wednesday 6 November 2024 at RAFA 2024 in Prague, Czech Republic. The session included new approaches for analysing per- and polyfluoroalkyl substances (PFAS), polychlorinated alkanes (PCAS), Mineral Oil Hydrocarbons (MOH), and short- and medium-chain chlorinated paraffins (SCCPs and MCCPs).
Advancing Bladder Cancer Research with Mass Spectrometry: A FeMS Interview with Marta Relvas-Santos
November 12th 2024LCGC International interviewed FeMS Empowerment Award winner Marta Relvas-Santos on her use of mass spectrometry to identify potential biomarkers and therapies for bladder cancer. She also shared insights on her work with FeMS and advice for fellow scientists.
