Clinical and Laboratory Standards Institute (CLSI) has recently published Mass Spectrometry in the Clinical Laboratory: General Principles and Guidance; Approved Guideline (C50-A) for the appropriate use of MS in the clinical laboratory.
Clinical and Laboratory Standards Institute (CLSI) has recently published Mass Spectrometry in the Clinical Laboratory: General Principles and Guidance; Approved Guideline (C50-A) for the appropriate use of MS in the clinical laboratory. Precise measurement approaches, methods verification, assay quality control, sample prep, instrument troubleshooting and interpreting results are all included in the new guide.
The guideline was developed in partnership with the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC).
LCGC’s Year in Review: Highlights in Liquid Chromatography
December 20th 2024This collection of technical articles, interviews, and news pieces delves into the latest innovations in LC methods, including advance in high performance liquid chromatography (HPLC), ultrahigh-pressure liquid chromatography (UHPLC), liquid chromatography–mass spectrometry (LC–MS), and multidimensional LC.
Using LC-MS/MS to Measure Testosterone in Dried Blood Spots
December 19th 2024Testosterone measurements are typically performed using serum or plasma, but this presents several logistical challenges, especially for sample collection, storage, and transport. In a recently published article, Yehudah Gruenstein of the University of Miami explored key insights gained from dried blood spot assay validation for testosterone measurement.