Scientists from Egypt, Sweden, Denmark, and India have collaborated to develop a computational tool to assess the environmental impact of high performance liquid chromatography (HPLC) methods.
Scientists from Egypt, Sweden, Denmark, and India have collaborated to develop a computational tool to assess the environmental impact of high performance liquid chromatography (HPLC) methods. Yassar Gaber, Ulrika Tornvall, Magdy Ali Amin, Rajni Hatti Kaul, and M.A. Kumar wrote that “This environmental assessment tool (EAT) takes into consideration the environmental, health and safety issues for all solvents involved in the chromatographic method, and calculates a total score that can be used for comparison of the greenness of different methods.”
The HPLC-EAT software can be downloaded for free at www.chromatographyonline.com and can also be combined with another free software eco-solvent tool to perform lifecycle assessments of waste disposal options (such as distillation or incineration).
The team explained the tool in detail in an article I the June 2011 issue of Green Chemistry.
For a recent discussion of green chemistry methods, see the R.E. Majors and D. Raynie article, “The Greening of the Chromatography Laboratory,” at
Best of the Week: Food Analysis, Chemical Migration in Plastic Bottles, STEM Researcher of the Year
December 20th 2024Top articles published this week include the launch of our “From Lab to Table” content series, a Q&A interview about using liquid chromatography–high-resolution mass spectrometry (LC–HRMS) to assess chemical hazards in plastic bottles, and a piece recognizing Brett Paull for being named Tasmanian STEM Researcher of the Year.
Using LC-MS/MS to Measure Testosterone in Dried Blood Spots
December 19th 2024Testosterone measurements are typically performed using serum or plasma, but this presents several logistical challenges, especially for sample collection, storage, and transport. In a recently published article, Yehudah Gruenstein of the University of Miami explored key insights gained from dried blood spot assay validation for testosterone measurement.
Determination of Pharmaceuticals by Capillary HPLC-MS/MS (Dec 2024)
December 19th 2024This application note demonstrates the use of a compact portable capillary liquid chromatograph, the Axcend Focus LC, coupled to an Agilent Ultivo triple quadrupole mass spectrometer for quantitative analysis of pharmaceutical drugs in model aqueous samples.