Investigating PFAS in Plastic Food Storage Bags Using Liquid Chromatography Tandem Mass Spectrometry (LC–MS/MS)

A recent study aimed to investigate the impact of lavender essential oil (LEO) and of its terpenic components on the properties of glioblastoma (GBM) cells in an in vitro model. The study demonstrated that LEO induces a proliferation slowdown and an impairment of cell migration of GBM cells besides reducing oxidative stress.

Peter Pellegrinelli, Applications Specialist at Advanced Materials Technology (AMT) explains the complexity of oligonucleotide separations due to the unique chemical properties of these molecules. Issues such as varying length, sequence complexity, and hydrophilic-hydrophobic characteristics make efficient separations difficult. Separation scientists are addressing these challenges by modifying mobile phase compositions, using varying ion-pairing reagents, and exploring alternative separation modes like HILIC and ion-exchange chromatography. Due to these complexities, AMT has introduced the HALO® OLIGO column, which offers high-resolution, fast separations through its innovative Fused-Core® technology and high pH stability. Alongside explaining the new column, Peter looks to the future of these separations and what is next to come.

A method to help detect genotoxic impurities (GTIs) using headspace gas chromatography (HS-GC) and deep eutectic solvents (DESs) has been developed.

This application note demonstrates the superior resolution and recovery of Agilent AdvanceBio SEC 500 Å columns when compared with competitor products for AAVs.