Electrophoretically Mediated Microanalysis of Creatinine
Researchers from Bucknell University (Lewisburg, Pennsylvania) used electrophoretically mediated microanalysis in a capillary tube to perform a Jaffe reaction between creatinine and picrate.
Researchers from Bucknell University (Lewisburg, Pennsylvania) used electrophoretically mediated microanalysis in a capillary tube to perform a Jaffe reaction between creatinine and picrate. They exercised careful control of the reagent plug length, concentration, and background electrolyte pH to improve analysis sensitivity. They used optimized conditions to successfully analyze three human serum samples across the expected clinical range of creatinine concentrations.
LCGC’s Year in Review: Highlights in Liquid Chromatography
December 20th 2024This collection of technical articles, interviews, and news pieces delves into the latest innovations in LC methods, including advance in high performance liquid chromatography (HPLC), ultrahigh-pressure liquid chromatography (UHPLC), liquid chromatography–mass spectrometry (LC–MS), and multidimensional LC.
Using LC-MS/MS to Measure Testosterone in Dried Blood Spots
December 19th 2024Testosterone measurements are typically performed using serum or plasma, but this presents several logistical challenges, especially for sample collection, storage, and transport. In a recently published article, Yehudah Gruenstein of the University of Miami explored key insights gained from dried blood spot assay validation for testosterone measurement.
