Biological, Medical, and Clinical Analysis

A recent paper discusses advances in hydrophilic interaction chromatography (HILIC) in the analysis of therapeutic oligonucleotides and their impurities.

Here are the top five articles that the editors of LCGC International published this week.

Scientists from the Lunan Pharmaceutical Group explored the use of UHPLC-MS/MS to test the effects of Shouhui Tongbian capsules (SHTBs) on slow transit constipation (STC).

Scientists from the Shenyang Pharmaceutical University in China have developed a new quality assessment system for various types of traditional Chinese medicine (TCM).

Scientists from Florida State University used Marfey’s reagent and reversed-phase liquid chromatography–tandem mass spectrometry (LC–MS/MS) to analyze D-amino acids.

Scientists from the University of Messina recently developed a new omega-3 fatty acid-based supplement and tested its effectiveness on metabolism and lipid profiles.

U.S. Environmental Protection Agency (EPA) Method 1633 signifies a pivotal shift in per- and polyfluoroalkyl substance (PFAS) determination, extending beyond drinking water.

Yelena Sapozhnikova from the United States Department of Agriculture spoke to The Column about her innovative research investigating PFAS in plastic food storage bags using targeted and non-targeted liquid chromatography–tandem mass spectrometry.

French scientists recently created a new analytical method for quantifying micropollutants in different species of gammarids.

This article discusses the importance of TIMS as it enhances the sensitivity, specificity, and speed of metabolite measurement, which in turn accelerates the pace of metabolomics research.

Here are the top five articles that the editors of LCGC International published this week.

Scientists from Hangzhou Medical College recently recorded the effectiveness of novel quality control strategies for the determination of vitamin D using liquid chromatography–tandem mass spectrometry (LC–MS/MS).

Scientists from China Pharmaceutical University developed a liquid chromatography-tandem mass spectrometry (LC–MS/MS)-based method for determining the presence of anti-colorectal cancer drugs in human plasma.

Swedish and German scientists recently made a new system for detecting of selective androgen receptor modulators (SARMs) in human samples.

Scientists from Anhui University of Chinese Medicine in Hefei, China recently investigated the mechanisms behind what makes huachansu tablets, a type of traditional Chinese medicine (TCM), effective against liver cancer.

Scientists from the Netherlands created a new LC–MS/MS assay to test new small molecular inhibitors (SMIs) and their effectiveness in prognosing lung cancer.

LCGC International sat down with Katarina Marakova to discuss her group’s work in top-down analysis of proteins using capillary zone electrophoresis–mass spectrometry (CZE–MS).

In this interview from Analytica 2024 in Munich, Germany, Michael Lämmerhofer of the University of Tuebingen discusses the potential of chiral stationary phases (CSPs) in different applications.

Here are the top five articles that the editors of LCGC International published this week.

Here are the top five articles that the editors of LCGC International published this week.

In a recent study, scientists evaluated different microextraction methods using green analytical chemistry (GAC) metrics.

In this edition of the LCGC Blog, Jonathan Edelman discusses the 43rd Annual International Symposium and Exhibit on the Separation, Purification, and Characterization of Biologically Important Molecules (ISPPP) and provides a timeline for the upcoming conference.

Here are the top five articles that the editors of LCGC International published this week.

A recent study out of Auburn University sought to further understand biological mechanisms at the molecular level using ion mobility spectrometry (IMS).

Joycelyn Tan, a PhD candidate at the University of Cambridge, is the 2024 recipient of the Darlene Solomon Award, co-sponsored by Females in Mass Spectrometry and Agilent Technologies, and created to provide support for up-and-coming women scientists.

Scientists recently tested a new system for detecting and extracting favipiravir from plasma samples.

Scientists from the Affiliated Hospital of Putian University recently analyzed the dysregulation of lipid metabolism in patients suffering from chronic hepatitis B patients.

Joycelyn Tan of the University of Cambridge recently won the Darlene Solomon Award for her notable research into mass spectrometry.

This week, LCGC International published a variety of articles on the hottest topics in chromatography and beyond. Below, we’ve highlighted some of the most popular articles, according to our readers. Happy reading!

This study explores the feasibility of using human skin volatile organic compounds (VOCs) analyzed through comprehensive gas chromatography–time of flight–mass spectrometry (GCxGC-TOF-MS) and chemometric techniques, to potentially serve as biomarkers for tuberculosis diagnosis.