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The 43rd International Symposium on Capillary Chromatography (ISCC) and the 16th GC×GC Symposium will return to Fort Worth, Texas, USA,-the “Gateway to the West”-in 2019.

Tips on how to extend high performance liquid chromatography (HPLC) column lifetimes.

Click the title above to open the LCGC North America November 2018 issue in an interactive PDF format.

Click the title above to open the LCGC North America November 2018 Special Issue, Advances in Food and Beverage Analysis, in an interactive PDF format.

What happens when we inject a sample into the mobile-phase stream? Many LC practitioners are surprised to learn just how serious the effect of the injected sample solvent can be.

Here, we focus on selectivity: its definition, its importance for generating separations and resolution; and its role in column polarity.

We assess the state of the field, first looking back at developments presented at conferences this year, reader questions, and the passing of a pioneer in solid-phase extraction. Then, we look to the future of sample preparation.

Scientists executing a method transfer often do not have access to the originating system. Thus, alternative approaches to matching chromatographic results must be considered.

The number of theoretical plates forms the basis of chromatographic theory, and is a key parameter used in all modes of chromatography for measuring column efficiency. Fortunately, it’s easy to measure.

Application of multivariate statistical analysis to a combined data set demonstrated that SIFT-MS discriminates premium quality beef from eight sensory defects, and, therefore, could be applied as an instrumental grading tool, obviating sensory panel grading.

This study assesses whether two commonly used plastic packaging materials are safe for use. Their potential migrants are analyzed using data-independent acquisition and liquid chromatography coupled with high-resolution, accurate-mass mass spectrometry.

The method described here is a simple method for detection of a wide spectrum of metals and for quantitative analysis over a wide dynamic range of elements, including both toxic metals and those metals essential for health and well-being.

A discussion of challenges in mycotoxin analysis, a new multi-analyte method that does not require sample cleanup, and how analytical chemistry can help reduce contamination by these toxins along the food chain.

Using highly specific immunoaffinity solid-phase extraction to selectively extract and enrich aflatoxins prior to HPLC-FLD analysis, without derivatization, low LOQ values-far below the European regulations-can be achieved even in highly complex and fatty matrices.

A new method enables quantification of pyrrolizidine alkaloids in a range of food matrices.

Unconventional oil and gas (UOG) extraction is a multistep process that involves horizontal drilling, hydraulic fracturing, and massive infrastructure to handle fossil fuel resource recovery and associated wastewater generation.

Click the title above to open The Column October 2018 North America issue in an interactive PDF format.

Click the title above to open The Column October 2018 European/Asia issue in an interactive PDF format.

Molar mass distributions, molar mass averages, and polydispersity can be determined by gel permeation chromatography (GPC), size-exclusion chromatography (SEC), and gel filtration chromatography (GFC). This makes this technique indispensable for all scientists in quality control (QC) and R&D who have to work with large molecules. However, the technical terms used can be quite confusing for beginners. This instalment of Tips & Tricks explains more.

Process chromatography, in particular process gas chromatography (GC), is a well‑established technique within the oil and gas, refining, and petrochemical industry. The technique is generally used in process plants to determine product quality and yield.

Waters Corporation has opened a new International Food and Water Research Centre (IFWRC) in Singapore to address the growing challenges of food and water security and safety.

Shimadzu has celebrated 50 years of Shimadzu in Europe with 300 guests attending an event in Duisburg, Germany, to commemorate the anniversary.

Incognito wonders if chromatographers are happy with their choice of career.

The Column spoke to Núria Fontanals, a senior researcher at the Department of Analytical and Organic Chemistry, Universitat Rovira i Virgili, Spain, about her work investigating the impact of artificial sweeteners as environmental pollutants using hydrophilic interaction chromatography (HILIC) and the broader role of HILIC in environmental analysis.

The goal of metabolite identification groups is to de-risk compounds moving into development by ensuring they have favourable metabolic profiles before clinical trials are initiated. Liquid chromatography–mass spectrometry (LC–MS) is a well-established technology for this purpose, as a result of its ability to selectively and accurately distinguish drugs and their metabolites. Ion mobility spectrometry (IMS) can add another critical dimension of separation by improving spectral clarity and generating collision cross section (CCS) values to track metabolites across multiple analysis conditions. Modern software platforms have now evolved to solidify the value of IMS for the field of metabolite identification.

The Column spoke to Linda Schreiner and Andrea Buettner of the Fraunhofer Institute for Process Engineering and Packaging IVV and the Friedrich-Alexander-Universität Erlangen-Nürnberg in Germany, about their work investigating Scots pine for odour-active compounds using two‑dimensional gas chromatography (2D-GC).

In peptide mapping, the enzymes and conditions used in digestion affect not only the number of peptides liberated, but also the stability of associated post-translational modifications (PTMs).