Helmut Ernstberger

The method described here is a simple method for detection of a wide spectrum of metals and for quantitative analysis over a wide dynamic range of elements, including both toxic metals and those metals essential for health and well-being.

Speciation analysis of elemental contaminants in food and beverages has received a lot of attention in recent years. Recent regulations limit inorganic arsenic, taking into account that arsenic toxicity is dependent on the species present. Thus, the analysis procedure needs to be able to differentiate inorganic from organic arsenic forms. Liquid chromatography–inductively coupled plasma–mass spectrometry (LC–ICP-MS) is commonly used for the separation and detection of arsenic species, with the most widely used implementation based on ion exchange and characterized by relatively long run times. Testing of increasing sample numbers means that analysis speed becomes a focal point for potential improvements. We developed a method based on ion interaction chromatography, allowing a reduction in run times to

Speciation analysis of elemental contaminants in food and beverages has received much attention in recent years. Recent regulations limit inorganic arsenic, taking into account that arsenic toxicity is dependent on the species present. The analysis procedure thus needs to be able to differentiate inorganic from organic arsenic forms. LC-ICP-MS is commonly used for separation and detection of arsenic species, with the most widely used implementation being based on ion exchange and characterized by relatively long run times. Testing of increasing sample numbers means that analysis speed becomes a focal point for potential improvements. We developed a method based on ion interaction chromatography, allowing a reduction in run times to