Cation-Exchange Separation of Proteins on a Bonded Hydrophilic Polymer-Coated Silica Support
Ion-exchange analysis of proteins.
Application Databases — Valuable Tools in Method Development
This note describes the use of an application database for developing LC and GC methods.
Faster Analysis and Higher Efficiency with Thermally Stable Column
Separation of antihistamines using a thermally stable HPLC column.
Analyzing Polymers by GC–MS Using Pyrolysis
GC–MS analysis of residual polystyrene in a pharmaceutical product.
Microwave-Assisted Extraction Using U.S. EPA Method 3546
Microwave-assisted extraction of pesticides, herbicides, semivolatile organic compounds, phenols, PCBs, and dioxins and furans.
Stability-Indicating HPLC Method Development — A Systematic Approach Using pH and Column Selectivity
Development of a stability-indicating HPLC method for paclitaxel.
Light-Guiding Fused-Silica Capillary Tubing
Fluoropolymer-coated synthetic fused-silica tubing for GC, capillary LC, and CE.
Efficient LC Separations of Proteins and Peptides for MS Analysis
Capillary LC–MS analysis of proteins and peptides.
Reversed-Phase HPLC Analysis of Sunscreen Compounds
Quality assurance analysis of sunscreen ingredients using reversed-phase HPLC.
Acrylate Monomers with SolGel-WAX
GC analysis of acrylate monomers.
MS Analysis of LC Fractions Using an Ettan LC–MS System
LC–MS analysis of proteins.
Ion-Exchange Analysis of Monoclonal Antibodies on Large-Pore TSK-GEL BioAssist Columns
Monoclonal antibody purification using ion-exchange LC.
Determination of Chloride in Acid Copper Plating Bath
Ion chromatography analysis of chloride concentration in a copper plating solution.
Characterization of RNase A Using SEC with Laser Light-Scattering, UV, and RI Detection Modes
Analysis of RNase A using size-exclusion chromatography with various detection modes.
On-Line MALS–QELS (Quasi-Elastic Light Scattering)
Combining multiangle light-scattering detection with quasi-elastic light-scattering detection for protein analysis.
Analysis of an Herbicide Using Anion-Exchange LC with Indirect Conductivity Detection
Herbicide analysis using ion-exchange LC.
Using Whelk-O for Chiral Method Development in Normal and Reverse Phase
Chiral separation of the pharmaceutical compounds warfarin and naproxen.
SEC–MALS of Low Molar Mass Compounds
Analysis of oligomers of epoxy resins and phenol–formaldehyde condensates using size-exclusion chromatography with multiangle light-scattering detection.
Microchip Electrophoresis and the Analysis of Polymerase Chain Reaction Products
The author compares chip-based electrophoretic methods with existing methods and competitors.
Pittcon Product Showcase
Products at Pittcon 2002.
Minimizing the Effect of Sample Preparation on Measurement Uncertainty
Guest author Veronika Meyer provides tips for decreasing measurement uncertainty caused by sample preparation.
Quiet, Please
John Dolan looks at chemical, physical, and electronic sources of baseline noise and suggests how to reduce or eliminate them.
Fifty Years of Gas Chromatography — The Pioneers I Knew, Part I
The first of a two-part series that discusses key pioneers of gas chromatography.
Intelligent Automation of LC–MS Analysis for the Characterization of Compound Libraries
This article reports an approach to applying intelligent automation for high-throughput LC}MS analysis of compound libraries using Microsoft Visual Basic software.
Determination of Phthalate Esters by Positive Chemical Ionization MS with Retention-Time Locked GC
The authors describe a new instrumental method for determining phthalate esters using positive chemical ionization and retention-time locking GC.
Nonlinearity in a Chromatographic System
This month's column discusses strategies for minimizing nonlinearity in gas chromatography.
Circulation Details
Circulation details
A Geometric Approach to Robustness Testing in Analytical HPLC
The authors describe a new approach for verifying robustness testing in HPLC.
Data Handling for Fast Chromatography — Peak Integration
"GC Connections" examines the basics of peak integration for quantitation in chromatography with an emphasis on fast separations.
The Benefits of Reversed Phases with Extended Polar Selectivity in Analyzing Wide-Polarity-Range Samples
This article describes the use of phases with extended polar selectivity to reduce analysis time for wide-polarity-range samples such as an insecticide, simulated carboxylic acid degradants, and phthalate esters.
