HPLC Determination of Artemisinin in Artemisia Annua L.
August 7th 2007In an article recently published in Analytica Chimica Acta, researchers developed a procedure for the determination of artemisinin in A. annua using high performance liquid chromatography (HPLC) with evaporative light scattering detection (ELSD) in couple with microwave-assisted extraction (MAE) as an efficient sample preparation technique. Afterwards, method validation system for HPLC?ELSD analysis was developed.
Chromatography Featured in Nova Episode
August 7th 2007In a story featured in the ?Hot Science? section on the website of the PBS television show Nova, chromatography is used as a method for analyzing residue at the World Trade Center site. The process of adsorption is described, and a link to a ?Color Separator Activity? is provided.
Improved Sample Prep for Protein Sorting
August 7th 2007In a recent issue of Nature Nanotechnology, a group of researchers from the Massachusetts Institute of Technology (Cambridge, Massachusetts) have created a microchip system capable of speeding up the separation and sorting of biomolecules such as proteins.
Discovery Channel Uses Chromatography to Find Authentic Tequilas
August 7th 2007The Discover Channel website reports that in response to the many counterfeit tequilas being produced today, researchers are using ion and gas chromatography to analyze tequila samples and compare them to the impure mixed "tequila" types. They found the authentic drink, which is regulated by strict standards in Mexico, has noticeably higher levels of certain chemicals, including methanol, 2-methyl-1-butanol, and 2-phenylethanol
Dr. Leroy Hood to Deliver Plenary Lecture at Pittcon 2008
August 6th 2007The Pittsburgh Conference announced today that Dr. Leroy Hood will deliver the plenary lecture, Systems Biology and Systems Medicine, during the Opening Session of Pittcon 2008 at the Ernest N. Morial Convention Center, New Orleans, LA on March 2, 2008.
Technology Forum: Software/LIMS
August 1st 2007This month's Technology Forum looks at the topic of Software/LIMS and the trends and issues surrounding it. Joining us for this discussion is Kim Shah, Director of Marketing and Business Development for Informatics at Thermo Fisher Scientific, John Helfrich Director of GMP Lab Automation Programs at VelQuest Corporation, and Donna Lococo, Enterprise Software Solutions Product Leader at PerkinElmer Life and Analytical Sciences.
Glossary of Terms Related to Chromatographic Method Validation
August 1st 2007One issue that has become clear to us throughout courses, workshops, seminars, and various talks on the subject of method validation, is that while many people talk the language, sometimes the individual method validation terms mean different things to different people. While the actual protocols, or experimental details used to measure or evaluate method validation can vary, it's a good idea to have a common understanding of the underlying terms. In this month's installment of "Validation Viewpoint," we have compiled glossary of method validation terms as they pertain to chromatography.
Thar Instruments Completes the Acquisition of Berger SFC
July 2nd 2007Thar Instruments, a global leader in the design, development and manufacture of Supercritical Fluid Chromatography (SFC) systems announced the acquisition of Berger SFC? division of METTLER TOLEDO. Berger SFC? is a pioneer in the development of SFC and a world leader in SFC Analysis and Purification.
Screening Acid-Base Constants by Capillary Electrophoresis
July 1st 2007The acid-base constants of the most frequently used antianginals (diltiazem, nadolol, propranolol and verapamil) were determined using capillary zone electrophoresis (CZE). This method is based on measuring the electrophoretic mobility of the solute as a function of pH. The buffer employed was composed of borate-phosphate buffered across the pH range of 3.0–11.2. The acid-base constants were determined by performing linear and non-linear regression on the data obtained. The results were compared with those reported in literature and with those obtained by a spectrophotometric method. After comparison of the values, no significant differences were observed between the three acid-base constants.