The LCGC Blog: An Excel Tutorial for Modelling Chromatographic Separations
September 5th 2013Chromatography can be approximated by a series of equilibrium events between the mobile phase and stationary phase. Here, LCGC Blog editor Kevin Schug discusses an exceptional spreadsheet macro written by an undergraduate researcher that helps users visualize the development of chromatographic separations.
Agilent Thought Leader Award to Support Web-Based Tools for Cancer and Drug-Safety Research
September 5th 2013Emmanuel Barillot, Director of Bioinformatics and Systems IT at the Institut Curie (Paris, France), has received an Agilent Thought Leader Award. Agilent will contribute financial support, products, and expertise to the work by Barillot to develop a database of cellular signalling pathways and a visualization tool to help the pharmaceutical industry develop more effective cancer treatments. The web-based tool will enable the identification of off-pathway effects of new drugs.
High-Resolution Mass Spectrometry: An Ideal Premier Analytical Tool for Drug Metabolism Studies
September 1st 2013In this instalment, a way of utilizing HR-MS systems to characterize the structures of metabolites is introduced. This results in a general workflow for metabolism studies for drug discovery and development.
The Essence of Modern HPLC: Advantages, Limitations, Fundamentals, and Opportunities
September 1st 2013The reasons that make HPLC so ubiquitous; the fundamentals on how we conduct HPLC separations; and a few opportunities with far-reaching impacts in life sciences for separation scientists are discussed in this article.