Capillary Liquid Chromatography - A Powerful Tool in Analytical Chemistry

Session: 650, Room S405a, 1:30 p.m.

This Monday afternoon session will be presided over by Stephen G. Weber, of the University of Pittsburgh (Pittsburgh, Pennsylvania).

The session will begin with a presentation by Luis A. Colon, of the University at Buffalo – SUNY (Buffalo, New York) titled “Nanoparticle Modified Monolithic Columns.” Colon’s presentation will focus on the details of column preparation, physicochemical characteristics, and preliminary chromatographic evaluation of these new types of monoliths.

Following Colon, James W. Jorgenson, of the University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) will present “High Resolution Separations by Capillary UHPLC.” Jorgenson will discuss a system for capillary UHPLC columns with operating pressures to 3400 bar (50,000 psi) and with elevated temperatures.

The next presentation in the session is titled “Prospects for Organic Monoliths in Capillary Liquid Chromatography” and will be delivered by Milton L. Lee, of Brigham Young University (Provo, Utah). The presentation will show how recent laboratory work using living polymerization methods have improved monolithic bed structures and resulted in chromatographic efficiencies for capillary LC in excess of 150,000 theoretical plates per meter.

Following a 15-minute recess, Frantisek Svec, of the Lawrence Berkeley National Laboratory (Berkeley, California) will present a talk titled “Monolithic Capillary Columns: Novel Approaches to Tuning Porosity and Pore Surface Chemistry.” Svec will discuss the recent development and demonstration of the second generation of monoliths using a new two-step approach to the control of porous properties that include hypercrosslinking reaction.

The final presentation in the session is scheduled to be given by Stephen G. Weber. Weber’s talk is titled “Increasing Capillary HPLC Speed” and will focus on the availability of higher pressure pumps and the recognition of temperature as an important variable in controlling band spreading and speed, leading to faster separations.