Application Notes

The identification benzodiazepine metabolites can be highly valuable in detecting abuse. Metabolites of oxazepam are found containing both hydroxyl and glucuronides.

This application note describes how Dow AgroSciences created efficiency in method development by incorporating method development software into their best practices.

Outlines an extraction procedure and an optional fluorenylmethyloxycarbonyl chloride derivatization step to allow for the analysis of glyphosate on a C18 column.

Improved and universal subunits LC–MS analysis of multiple classes of monoclonal antibodies using in-line electrochemical reduction  

Daicel Chiral Technologies' unique HPLC and SFC chiral stationary phases are capable of separating the most challenging compounds, like the atropisomers of Sotorasib.

Smart-ramped pyrolysis-GC–MS analysis of forensic samples such as paint, adhesive tape, and mascara gives maximum info in a single run without method development.

Smart-ramped pyrolysis-GC–MS analysis of nylon material in consumer products, food packaging, and clothing generates info in one run without method development.

Smart-ramped pyrolysis-GC–MS analysis of (meth)acrylates in consumer products, caulk, and nail hardener gives maximum info in a single run without method development.

Solvent-free extraction by passive sampling using TF-SPME and HSSE, and by active pumped sampling onto sorbent tubes, are compared for TD-GC–MS analysis of volatiles.

Olfactory detection of sensory-active compounds guides GC–MS analysis for efficient flavour assessment of foodstuffs and their plant-based replacement products.

Solvent-free extraction and analyte concentration using TF-SPME and SBSE are optimized for TD-GC–MS determination of flavour compounds in hard seltzer beverages.

This study demonstrates the use of pyrolysis-(GC¬–)MS to generate simulated TGA-MS data for polymers. The mode of operation is also referred to as evolved gas analysis.

Smart-ramped pyrolysis-GC¬–MS analysis of microplastics in water filtration residue gives maximum info in one run. Examples are runoff, grey-, pond-, and bottled water.

A micro-scale chamber method performs DNPH derivatization and Tenax TA sorption for analysis of formaldehyde and carbonyl compounds by LC–UV, and VOCs by GC–MS.

This application note shows that a single column to be used for the analysis of a wide range of molecular sizes, from intact proteins and monoclonal antibodies to digested peptides.

This application note describes the benefits of automated gravimetric liquid dispensing compared to traditional manual stock solution preparation in a volumetric flask.

This application note examines a group of UHPLC columns and their analytical conditions using synthesized miRNA samples.

Here, we introduce HPLC columns with wider pores designed to analyze the characterization of the first-dimensional structure of peptides in reverse phase condition.

This application note introduces the usefulness of wide pore columns, targeting large macromolecules.

This guide describes how you can improve the efficiency of your chromatographic workflow with our manual, automated, and robotic solutions

Application of C18, 1.6 µm UHPLC columns in the analysis of insulin with strong and weak ion pairing agents to see how they increase the height of the insulin peak.

This application note covers high-resolution oligonucleotide analysis using a wide pore (WP) C18 1.6 µm UHPLC column.

This application note explains an integrated workflow with automatic flow of weighing data from sample and standard preparation to chromatographic analysis in the HPLC.

Read our application note to find out how gravimetric solution preparation can significantly reduce the cost of your trace metal analyses.

This application note describes the benefits of using a fully automated robotic solution for preparing samples and standards for chromatographic analyses.

This application note presents a quick and easy way to prepare accurate reference standards for HPLC and other chromatographic (analytical) methods.

This application note introduces application data obtained by using FlexFire SEC Columns that have adopted newly developed superior silica.