Application Notes

In this note, the molecular weight averages and molecular weight distributions of two hydroxyethyl starch (HES) samples were successfully demonstrated.

This application note details two UCT sample preparation approaches (SPE and QuEChERS) that can be used for the extraction and clean-up of mycotoxins from grain-based food.

Reagent free reduction of protein disulfide bond without the use of interfering DTT or TECP for superior peptide sequencing and S-S bond assignment.

Reagent free reduction of protein disulfide bond without the use of interfering DTT or TECP for superior peptide sequencing and S-S bond assignment.

Electrochemical simulation of phase I metabolism of 3 novel cardiovascular drugs and comparison with in-vivo data (human urine) reveals the power of EC-MS

New electrochemical cell for on-line reduction of disulfide bonds in HDXMS with significant higher sequence coverage than TECP reduction.

New electrochemical cell for on-line reduction of disulfide bonds in HDXMS with significant higher sequence coverage than TECP reduction.

Electrochemical oxidation for fast mimicking of phase I metabolism of Triclosan and its transformation products including their synthesis for toxicological evaluation.

Rapid and cost-effective synthesis of mg quantities of metabolites or reference materials for comprehensive structural identification by MS, NMR or for toxicology studies.

Electrochemical oxidation for fast mimicking of phase I metabolism of Triclosan and its transformation products including their synthesis for toxicological evaluation.

Rapid and cost-effective synthesis of mg quantities of metabolites or reference materials for comprehensive structural identification by MS, NMR or for toxicology studies.

Electrochemical simulation of phase I metabolism of 3 novel cardiovascular drugs and comparison with in-vivo data (human urine) reveals the power of EC-MS

Analysis of monocyclic aromatic hydrocarbons in accordance with ASTM method D7504 with the Agilent 8890 GC and DB-Heaver Wax Columns

Strata-X PRO was chosen to extract a panel of acids, neutrals, and bases from plasma. This simple method eliminates time-consuming method development and recovery for extremely polar analytes.

Using Strata-X PRO to extract barbiturates from serum saves time by reducing the method to 3 quick and easy steps. In addition, the matrix is more effectively clean-up vs protein precipitation.

Strata-X PRO consists of a new type of polymeric SPE sorbent combined with matrix removal technology to revolutionize sample extractions and matrix clean-up by eliminates the conditioning and equilibration steps.

This application displays that for a range of pain relievers, an easy 3-Step SPE method can be implemented and produce high recoveries.

When working with milk as a matrix, Strata-X PRO SPE removes phospholipids more efficiently than traditional SPE to reduce any ion suppression that may occur during LC-MS/MS analysis.

Strata-X PRO consists of a new type of polymeric SPE sorbent combined with matrix removal technology to revolutionize sample extractions and matrix clean-up by eliminates the conditioning and equilibration steps.

When working with milk as a matrix, Strata-X PRO SPE removes phospholipids more efficiently than traditional SPE to reduce any ion suppression that may occur during LC-MS/MS analysis.

This application displays that for a range of pain relievers, an easy 3-Step SPE method can be implemented and produce high recoveries.

Strata-X PRO was chosen to extract a panel of acids, neutrals, and bases from plasma. This simple method eliminates time-consuming method development and recovery for extremely polar analytes.

In this webinar, learn how to achieve cleaner, more concentrated, and targeted sample preparation methods to help with downstream analysis for both analytical and biopharmaceutical labs.

For this peptide application, two different types of polymeric SPE (WCX and SAX) were tested in parallel with Strata-X PRO SPE and compared in regards to recovery and % variation.

In this webinar, learn how to achieve cleaner, more concentrated, and targeted sample preparation methods to help with downstream analysis for both analytical and biopharmaceutical labs.

For this peptide application, two different types of polymeric SPE (WCX and SAX) were tested in parallel with Strata-X PRO SPE and compared in regards to recovery and % variation.

Using Strata-X PRO to extract barbiturates from serum saves time by reducing the method to 3 quick and easy steps. In addition, the matrix is more effectively clean-up vs protein precipitation.

Proper filtration is essential for ensuring reliable performance of high performance liquid chromatography (HPLC) instruments. In this ebook, on Modern Filtration Methods for HPLC and UHPLC Sample Preparation, explore: • Tips for mobile phase filtration • Answers to FAQs about syringe filter selection • Why filtration is so important to method development and sample prep • Filters for sample prep in dissolution testing

• Applications of native mass spectrometry • Implementation and technical challenges with native MS