Application Notes

Electrochemical oxidation for fast mimicking of phase I metabolism of Triclosan and its transformation products including their synthesis for toxicological evaluation.

Rapid and cost-effective synthesis of mg quantities of metabolites or reference materials for comprehensive structural identification by MS, NMR or for toxicology studies.

Electrochemical simulation of phase I metabolism of 3 novel cardiovascular drugs and comparison with in-vivo data (human urine) reveals the power of EC-MS

Analysis of monocyclic aromatic hydrocarbons in accordance with ASTM method D7504 with the Agilent 8890 GC and DB-Heaver Wax Columns

Strata-X PRO was chosen to extract a panel of acids, neutrals, and bases from plasma. This simple method eliminates time-consuming method development and recovery for extremely polar analytes.

Using Strata-X PRO to extract barbiturates from serum saves time by reducing the method to 3 quick and easy steps. In addition, the matrix is more effectively clean-up vs protein precipitation.

Strata-X PRO consists of a new type of polymeric SPE sorbent combined with matrix removal technology to revolutionize sample extractions and matrix clean-up by eliminates the conditioning and equilibration steps.

This application displays that for a range of pain relievers, an easy 3-Step SPE method can be implemented and produce high recoveries.

When working with milk as a matrix, Strata-X PRO SPE removes phospholipids more efficiently than traditional SPE to reduce any ion suppression that may occur during LC-MS/MS analysis.

Strata-X PRO consists of a new type of polymeric SPE sorbent combined with matrix removal technology to revolutionize sample extractions and matrix clean-up by eliminates the conditioning and equilibration steps.

When working with milk as a matrix, Strata-X PRO SPE removes phospholipids more efficiently than traditional SPE to reduce any ion suppression that may occur during LC-MS/MS analysis.

This application displays that for a range of pain relievers, an easy 3-Step SPE method can be implemented and produce high recoveries.

Strata-X PRO was chosen to extract a panel of acids, neutrals, and bases from plasma. This simple method eliminates time-consuming method development and recovery for extremely polar analytes.

In this webinar, learn how to achieve cleaner, more concentrated, and targeted sample preparation methods to help with downstream analysis for both analytical and biopharmaceutical labs.

For this peptide application, two different types of polymeric SPE (WCX and SAX) were tested in parallel with Strata-X PRO SPE and compared in regards to recovery and % variation.

In this webinar, learn how to achieve cleaner, more concentrated, and targeted sample preparation methods to help with downstream analysis for both analytical and biopharmaceutical labs.

For this peptide application, two different types of polymeric SPE (WCX and SAX) were tested in parallel with Strata-X PRO SPE and compared in regards to recovery and % variation.

Using Strata-X PRO to extract barbiturates from serum saves time by reducing the method to 3 quick and easy steps. In addition, the matrix is more effectively clean-up vs protein precipitation.

Proper filtration is essential for ensuring reliable performance of high performance liquid chromatography (HPLC) instruments. In this ebook, on Modern Filtration Methods for HPLC and UHPLC Sample Preparation, explore: • Tips for mobile phase filtration • Answers to FAQs about syringe filter selection • Why filtration is so important to method development and sample prep • Filters for sample prep in dissolution testing

• Applications of native mass spectrometry • Implementation and technical challenges with native MS

It is important for the standards, organic solvents, and HPLC mobile phases to be of the highest purity, but water quality is often taken for granted.

Essential oils have been a staple of the food, fragrance, and health markets for many years. Owing to their unique composition, essential oils can be used for a variety of applications

Note discusses how labs can streamline operations and cut costs with on-sit gas generation.

• FFF–MALS offers deep and unbiased particle characterization. • Regulatory bodies view FFF–MALS as essential for various nanomedicines.

• Parameter variety adds complexity to analytical method development. • Reversed-phase HPLC offers an efficient approach to simply this process.

• Transferring from HPLC to UHPLC comes with both benefits and costs. • Making the transition more predictable can boost efficiency. • Informed equipment and procedural decisions can combat transfer challenges.

The EAF4 system was used to measure the electrophoretic mobility and zeta potential of 50 nm Ag nanoparticles (AgNPs) coated with three different coating materials.

The EAF4 system was used to measure the electrophoretic mobility and zeta potential of 50 nm Ag nanoparticles (AgNPs) coated with three different coating materials.