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SEC-MALS for absolute biophysical characterization
SEC-MALS analyzes proteins, peptides, nucleic acids, polysaccharides and bionanoparticles to determine molar mass, size, conjugation, aggregation and interactions.
Applying High-Resolution and High-Efficiency Size Exclusion Chromatography Technology to Biotherapeutic Characterization
• Challenges and solutions for getting the most accurate data from SEC • Combining SEC with UV or MS detection to quickly analyze samples
Analysis of Formoterol, Budesonide, and Related Compounds by UPLC–MS
Explore the analytical potential of the AQbD approach for achieving high-performance separations of formoterol, budesonide, and its related compounds.
Increasing Recovery of Trace-Level Fatty Acid Analytes
The benefits of using QuanRecovery Vials for trace analysis of fatty acids in RPLC-MS based workflows.
Automated Analytical Cation-Exchange Chromatography
In this application note, infliximab and trastuzumab were separated on a BioResolve SCX mAb Column, and their charge variant fractions were collected using a Waters Fraction Manager-Analytical (WFM-A).
A Method for the Quantitative Determination of Pesticide Residues
The development and validation of a robust, quantitative method for the routine determination of a wide range of LC-amenable pesticides following QuEChERS (DisQuE dispersive sample preparation) procedure and LC-MS/MS
HRMS System Check for Intact Protein Quantification
This document is designed to help the user performing intact and/or subunit protein analysis evaluate the performance or suitability of the instrument by undertaking a simple system check (SC) and running of QC standards.
Vivaspin®: Concentration to a Defined Volume
Describes a method for reproducible defined final volumes using several Vivaspin® centrifugal concentrators: Turbo 15, Turbo 4, and 500.
Desalting and Buffer Exchange with Vivaspin® Centrifugal Concentrators
Outlines desalting or buffer exchange processes for Vivaspin concentrators to allow a significant reduction in salt concentration without diluting the protein sample.
Vivaspin® Concentrators for Low-Concentrated Protein Samples
Outlines a pre-treatment process for Vivaspin concentrators to improve recovery of very dilute protein samples in the nano- to microgram concentration range.
A Revolutionary Approach to Light Scattering Technology
• Enhanced sensitivity and range are needed to obtain molecular weight and size. • New light scattering detector addresses flaws of traditional approaches.
Targeted and Untargeted Forensic Screening Methods by Gas Chromatography-Mass Spectrometry for Anti-Doping and Forensic Toxicological Purposes
• Methods for sports doping control using high resolution mass spectrometry • Using HRMS, one GC–MS and LC–MS method offers efficient, accurate screening
Automated LC Method Development and Robustness Tests
This technical overview demonstrates automated method development of pharmaceutical samples using the Agilent 1290 Infinity II LC combined with ChromSwordAuto software.
Significantly Improving Robustness of PAH Analysis in Palm Oil
Fast Analysis Workflow with No Sample Preparation for Forensic Applications Using QuickProbe GC/MS
EU Priority PAH Analysis in Pumpkin Seed Oil Using Bond Elut EMR–Lipid Cleanup by GC/MS/MS
Agilent JetClean: In-situ GC/MS Ion Source Cleaning and Conditioning
Scientific Poster: Sub-minute Analysis for Samples of Forensic Applications
Phthalates Analysis with Method GB 5009.271-2016 Using the Agilent 8890 GC and MSD with Agilent JetClean
Does Your Electronic Data System Meet 21 CFR Part 11 and CGMP Requirements?
• Know and understand your electronic data system and workflow • Log entries generated by an analytical data system and a typical workflow
Chemistry of Wine
