Gyula Vigh, professor of chemistry and holder of the Gradipore Chair of Separation Science at Texas A&M University (College Station, Texas) will be recognized for his research excellence in the separation sciences with the 2011 Halász Medal in June.
Gyula Vigh, professor of chemistryand holder of the Gradipore Chair ofSeparation Science at Texas A&M University(College Station, Texas) will berecognized for his research excellencein the separation sciences with the2011 Halász Medal in June. The awardsceremony will take place during the36th International Symposium on HighPerformance Liquid Phase Separationsand Related Techniques, June 19–23, inBudapest, Hungary.
Created in 1997, the award is inmemory of István Halász, an expert ingas chromatography and pioneer inliquid chromatography. It was set upto commend researchers for outstandingachievements in or contributionsto the study of separation science, ortechniques used to separate differenttypes of substances and to purify,quantify, and identify the individualcomponents.
“I was very surprised, as I didn’teven know I had been nominated,”Vigh told the Texas A&M news service.“It’s very humbling and verypleasurable to receive the same awardas some of the guys who helpedestablish our science.”
Past recipients of the award includeYale University’s Csaba Horváth, theinaugural recipient and star pupil ofIstván Halász himself; the University ofTennessee’s Georges Guiochon; BarryKarger of Northeastern University;Uwe Neue of Waters Corporation; andWolfgang Lindner of the Universityof Vienna.
Vigh also is scheduled to present aplenary lecture entitled “A New Preparative-Scale Isoelectrophoretic TrappingDevice: Design, Construction, andFirst Characterization,” explaining atechnique developed in his laboratory.
Vigh has been a member of theTexas A&M faculty since 1985, and hisresearch focuses on analytical chemistry— specifically electrophoresis, themovement of charged particles in afluid or gel under the influence of anelectric field. His laboratory is currentlyinvestigating isoelectric trapping of ampholytic substances within a deviceto achieve separation — a vital tool inthe purification process for a wide varietyof substances, from medications toproteins, in a host of applications.
The Complexity of Oligonucleotide Separations
January 9th 2025Peter Pellegrinelli, Applications Specialist at Advanced Materials Technology (AMT) explains the complexity of oligonucleotide separations due to the unique chemical properties of these molecules. Issues such as varying length, sequence complexity, and hydrophilic-hydrophobic characteristics make efficient separations difficult. Separation scientists are addressing these challenges by modifying mobile phase compositions, using varying ion-pairing reagents, and exploring alternative separation modes like HILIC and ion-exchange chromatography. Due to these complexities, AMT has introduced the HALO® OLIGO column, which offers high-resolution, fast separations through its innovative Fused-Core® technology and high pH stability. Alongside explaining the new column, Peter looks to the future of these separations and what is next to come.
Metabolomics Analysis of Low Birth-Weight Infants Using UHPLC-MS/MS Following Lipid Emulsion
January 10th 2025A recent study aimed to directly compare the changes in serum metabolites among very low birth-rate (VLBW) infants following the administration of the soybean oil-based lipid emulsion and soybean oil, medium-chain triglycerides, olive oil, and fish oil (SMOF) lipid emulsion using untargeted metabolomics techniques.
Analyzing New Drug Modalities: An ISC 2024 Interview with Kelly Zhang
January 10th 2025At ISC 2024 in Liverpool, United Kingdom, LCGC International interviewed Kelly Zhang of Genentech about her work analyzing new drug modalities, such as mRNA, oligonucleotides, peptides, and cell and gene therapies.