Thermo Scientific SOLA SPE Cartridges and Plates
Thermo Scientific SOLA products revolutionize Solid Phase Extraction (SPE). This first fritless SPE product range provides greater reproducibility with cleaner, more consistent extracts.
Thermo Scientific SOLA products provide unparalleled performance characteristics compared to conventional SPE, phospholipid removal and protein precipitation products.
This includes:
The proprietary manufacturing process involved in the production of SOLA™ products provides an SPE product which eliminates issues normally associated with conventional loose-packed SPE products, by combining the polyethylene frit material and media components into a uniform sorbent bed, removing the need for frits.
The increased performance delivered by SOLA products provides higher confidence in analytical results and lowers cost without compromising ease of use or requiring complex method development.
In today’s high throughput laboratory environment where reproducibility, certainty of results and cost saving is a fundamental requirement, SOLA products are an indispensible tool to provide confidence and first time/every time success in the analytical process.
Learn more at ref="http://www.thermoscientific.com/sola-spe">www.thermoscientific.com/sola-spe
The Complexity of Oligonucleotide Separations
January 9th 2025Peter Pellegrinelli, Applications Specialist at Advanced Materials Technology (AMT) explains the complexity of oligonucleotide separations due to the unique chemical properties of these molecules. Issues such as varying length, sequence complexity, and hydrophilic-hydrophobic characteristics make efficient separations difficult. Separation scientists are addressing these challenges by modifying mobile phase compositions, using varying ion-pairing reagents, and exploring alternative separation modes like HILIC and ion-exchange chromatography. Due to these complexities, AMT has introduced the HALO® OLIGO column, which offers high-resolution, fast separations through its innovative Fused-Core® technology and high pH stability. Alongside explaining the new column, Peter looks to the future of these separations and what is next to come.
Metabolomics Analysis of Low Birth-Weight Infants Using UHPLC-MS/MS Following Lipid Emulsion
January 10th 2025A recent study aimed to directly compare the changes in serum metabolites among very low birth-rate (VLBW) infants following the administration of the soybean oil-based lipid emulsion and soybean oil, medium-chain triglycerides, olive oil, and fish oil (SMOF) lipid emulsion using untargeted metabolomics techniques.
Analyzing New Drug Modalities: An ISC 2024 Interview with Kelly Zhang
January 10th 2025At ISC 2024 in Liverpool, United Kingdom, LCGC International interviewed Kelly Zhang of Genentech about her work analyzing new drug modalities, such as mRNA, oligonucleotides, peptides, and cell and gene therapies.
