Re-think the way your lab operates with the Thermo Scientific ISQ single quadrupole GC-MS system. The ISQ? GC-MS incorporates a source design that lets your system stay cleaner, longer. With heat throughout the ion optics, the ISQ GC-MS system can analyze more dirty samples per day, with maximum uptime.
Unstoppable Productivity
The Thermo Scientific ISQ single quadrupole GC-MS system offers rugged and reliable performance and nonstop productivity. The ISQ GC-MS system provides simplified operation and minimum downtime for uninterrupted productivity in routine GC-MS applications including forensics, toxicology, food safety and environmental. A highly robust and rugged system, the ISQ GC-MS features the new ExtractaBrite™ removable ion source designed to provide maximum uptime and productivity by increasing the length of time between required source maintenance. In addition, the ISQ GC-MS offers the ability to remove the entire ion source without venting the analyzer to allow 24/7 operation.
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The Complexity of Oligonucleotide Separations
January 9th 2025Peter Pellegrinelli, Applications Specialist at Advanced Materials Technology (AMT) explains the complexity of oligonucleotide separations due to the unique chemical properties of these molecules. Issues such as varying length, sequence complexity, and hydrophilic-hydrophobic characteristics make efficient separations difficult. Separation scientists are addressing these challenges by modifying mobile phase compositions, using varying ion-pairing reagents, and exploring alternative separation modes like HILIC and ion-exchange chromatography. Due to these complexities, AMT has introduced the HALO® OLIGO column, which offers high-resolution, fast separations through its innovative Fused-Core® technology and high pH stability. Alongside explaining the new column, Peter looks to the future of these separations and what is next to come.
Metabolomics Analysis of Low Birth-Weight Infants Using UHPLC-MS/MS Following Lipid Emulsion
January 10th 2025A recent study aimed to directly compare the changes in serum metabolites among very low birth-rate (VLBW) infants following the administration of the soybean oil-based lipid emulsion and soybean oil, medium-chain triglycerides, olive oil, and fish oil (SMOF) lipid emulsion using untargeted metabolomics techniques.
Analyzing New Drug Modalities: An ISC 2024 Interview with Kelly Zhang
January 10th 2025At ISC 2024 in Liverpool, United Kingdom, LCGC International interviewed Kelly Zhang of Genentech about her work analyzing new drug modalities, such as mRNA, oligonucleotides, peptides, and cell and gene therapies.