The Answer is Digitization — What are the Questions OR How to Hit Two Birds with One Stone.
Aimed at GMP-regulated laboratories, this podcast discusses the regulatory and business drivers for digitizing analytical processes, how they go hand in hand, and some practical aspects on how to approach such a journey. The business benefits of improving laboratory efficiency by releasing product earlier, and technical controls to ensure regulatory compliance, should easily justify automation projects. It is crucial to automate now under your own timeline rather than be forced by regulatory citations.
SPE-Based Method for Detecting Harmful Textile Residues
January 14th 2025University of Valencia scientists recently developed a method using solid-phase extraction (SPE) followed by high-performance liquid chromatography coupled to high-resolution mass spectrometry (HPLC–HRMS/MS) for detecting microplastics and other harmful substances in textiles.
The Complexity of Oligonucleotide Separations
January 9th 2025Peter Pellegrinelli, Applications Specialist at Advanced Materials Technology (AMT) explains the complexity of oligonucleotide separations due to the unique chemical properties of these molecules. Issues such as varying length, sequence complexity, and hydrophilic-hydrophobic characteristics make efficient separations difficult. Separation scientists are addressing these challenges by modifying mobile phase compositions, using varying ion-pairing reagents, and exploring alternative separation modes like HILIC and ion-exchange chromatography. Due to these complexities, AMT has introduced the HALO® OLIGO column, which offers high-resolution, fast separations through its innovative Fused-Core® technology and high pH stability. Alongside explaining the new column, Peter looks to the future of these separations and what is next to come.
