In a market as dynamic and fast-paced as ours, it should come as no surprise that in the months since I last addressed our readers in this space, a great deal has taken place in the world at large and in the field of separation science in particular.
In a market as dynamic and fast-paced as ours, it should come as no surprise that in the months since I last addressed our readers in this space, a great deal has taken place in the world at large and in the field of separation science in particular. Many issues that dominated the headlines just a few short months ago have now evolved and given way to new issues that may require new solutions.
Michael J. Tessalone
At LCGC, we continue to believe as we always have, that the notes contained in The Application Notebook are something of a microcosm of the marketplace, reflecting the ongoing and evolving issues that face chromatographers every day, and this edition is no exception. With the biotech industry continuing to make strides, you will see numerous application notes across this field, including many on biopharmaceuticals. With concerns over the long-term price of acetonitrile now beginning to replace supply considerations in many minds, you will find notes that offer new and innovative ways to conserve solvent. With food safety continuing to be a major concern in the U.S. and world markets, more stringent testing is being implemented, and here you will find corresponding application notes with new and better food testing methods, created in large part to meet this challenge.
In short, if you are experiencing an issue in your lab or business, chances are you will find it being addressed in one of the application notes contained in this issue. And if by some chance you do not, then please feel free to let us know. We rely on your feedback to help us shape future content and projects down the road, so do not hesitate to contact myself or any of our staff at the listings found in the masthead.
Enjoy the issue.
Michael J. Tessalone
Science Group Publisher
Characterization and Assessment of Effects of Drying Temperature on Edible Mushrooms with HS-GC–MS
September 6th 2024To gain insight into the effect of drying temperature on its composition, headspace solid-phase microextraction-gas chromatography-mass spectrometry (HS-SPME-GC–MS) was used for the identification of volatile organic compounds (VOCs) of 86 mushroom samples that were divided into five groups and dried at different temperatures.
Modern HPLC Strategies: Improving Retention and Peak Shape for Basic Analytes
August 16th 2024In high-performance liquid chromatography (HPLC), it is common for bases and unreacted ionized silanols on silica-based columns to cause irreproducible retention, broad peaks, and peak tailing when working with basic analytes. David S. Bell, Lead Consultant at ASKkPrime LLC offers innovative HPLC strategies that can help mitigate such issues.
Real-Time Measurement of EPA Regulated HON Compounds and Environmental Pollutants Using SIFT-MS
September 6th 2024This application note describes the determination of method detection limits (MDLs) for the newly regulated HON (Hazardous Organic NESHAP) compounds, which validate SIFT-MS as an effective solution for measuring these toxic VOCs and other environmental pollutants in ambient air, whether at the fence line or in a mobile setting.