News from the chromatography industry.
Millipore completes acquisition of Serologicals
Millipore Corporation (Billerica, Massachusetts) announced that it has completed its acquisition of Serologicals following approval by Serologicals' shareholders last week. The acquisition will transform Millipore into a life science company with combined annual revenues of approximately $1.4 billion, based on 2006 full year projections.
The combined organization of approximately 5800 employees also will have significantly expanded R&D capabilities with more than 500 R&D professionals worldwide.
Neue and Molnar awarded at symposium
The 6th Balaton Symposium on High-Performance Separation Methods was held in Siofok, Hungry. The first Balaton Conference in 1955 was sponsored by the Chromatographic Group of the Hungarian Chemical Society. In the past ten years, the society has increased in size and international recognition. The symposium included more than 30 oral and nearly 140 poster presentations with more than 360 registered delegates from 23 countries.
During the symposium, several individuals were recognized for their accomplishments in the field of separation science. Director of External Research at Waters Corporation (Milford, Massachuetts) and LCGC author and reviewer Uwe D. Neue was presented with the 2005 Halasz Medal Award. Imre Molnar of the Molnar Research Institute (Berlin, Germay) and a previous member of the LCGC editorial board, was presented with the 2005 Csaba Horvath memorial Award.
Thermo launches on-line chromatography resource center
Thermo Electron Corporation (Waltham, Massachusetts) has developed a new web-based chromatography resource center to provide tools and technical advice to chromatographers. The chromatography resource center is readily accessible via http://www.thermo.com/columns.
Beckman Coulter adopts ARTEL technology
ARTEL announced that Beckman Coulter has adopted the ARTEL MVS (Multichannel Verification System) to verify the accuracy and precision of its automated liquid handling systems used in pharmaceutical and clinical laboratories. As part of Beckman Coulter's Field Service Operational Qualification Program, the MVS provides solid documentation about system performance, helping laboratories meet compliance and regulatory requirements.
Determining Neurotransmitters in Spinal Cords with UHPLC
February 18th 2025Researchers at Jilin University (Changchun, China) developed a highly sensitive, rapid, and accurate method for analyzing neurotransmitters (NTs) in rat spinal cord tissue. Ultra-high performance liquid chromatography-triple quadrupole tandem mass spectrometry (UHPLC-QqQ-MS/MS) in conjunction with ultra-ionic liquid dispersive liquid-liquid microextraction (UA-MIL-DLLME) were used to extract NTs for analysis.
The Next Frontier for Mass Spectrometry: Maximizing Ion Utilization
January 20th 2025In this podcast, Daniel DeBord, CTO of MOBILion Systems, describes a new high resolution mass spectrometry approach that promises to increase speed and sensitivity in omics applications. MOBILion recently introduced the PAMAF mode of operation, which stands for parallel accumulation with mobility aligned fragmentation. It substantially increases the fraction of ions used for mass spectrometry analysis by replacing the functionality of the quadrupole with high resolution ion mobility. Listen to learn more about this exciting new development.
Revolutionizing LC-MS with Next-Gen Separation for Cyclic Peptide Analysis
February 17th 2025Cyclic peptides, known for their stability and high specificity, are promising therapeutic agents in the fight against cancer, infections, and autoimmune diseases. However, developing effective cyclic peptides presents numerous challenges, including poor pharmacokinetics, efficacy, and toxicity. Traditional methods like liquid chromatography tandem-mass spectrometry (LC-MS/MS) often struggle with resolving isomeric linear peptide metabolites, posing significant risks in safety, efficacy, and regulatory approval. In this paper, Komal Kedia, PhD, will share how she leveraged MOBIE’s high-resolution ion mobility-mass spectrometry (IM-MS) system to achieve a 72% reduction in run times, 200% greater resolving power, and enhanced accuracy in identifying “soft spots” prone to enzymatic degradation.