Controlling Retention in Liquid Chromatography with New Stationary Phases, Temperature, and Modeling
This morning session, to be held in Room 122A and with Sarah Rutan of Virginia Commonwealth University (Richmond, Virginia) presiding, begins at 8:30 am.
A morning session on controlling retention in liquid chromatography, to be held in Room 122A and with Sarah Rutan of Virginia Commonwealth University presiding, begins at 8:30 am with Anna Forzano, also of Virginia Commonwealth University, speaking on “C8-Ammonium Multicomponent Stationary Phase Gradients on Silica Particle Columns for Strong Anion Exchange and Reversed Phase Liquid Chromatography.”
At 8:50 am, “Multiplicative On-Column Solute Focusing Using Spatially Dependent Temperature Programming for Capillary HPLC” will be presented by Michael Rerick of the University of Pittsburgh.
“Surface Modification of Superficially Porous Silica Particles for HPLC via Diazotization and ‘Craft Knitting’,” by Luis Colon of the University at Buffalo, SUNY, is scheduled for 9:10 am, followed by Erin Shields of the University of Pittsburgh speaking on “pH Stable Liquid Chromatography Stationary Phases Made Using the Thiol-yne Reaction.”
Yong Guo of Fairleigh Dickinson University’s School of Pharmacy will present “A Closer Look at the Retention of Polar Compounds in Hydrophilic Interaction Chromatography (HILIC)” at 10:05 am, to be followed by “Evaluation of Three Temperature- and Mobile Phase-Dependent Retention Models for Reversed-Phase Liquid Chromatography,” presented by Anthony Horner of the University of Pittsburgh at 10:25 am. Next, chairperson Rutan will speak on “Closed Form Expressions for Retention Time and Peak Width in Gradient Liquid Chromatography Based on Linear Solvent Strength and Neue-Kuss Models” at 10:45 am.
The session concludes with “Evaluation of Chromatography Fundamentals Applied to Weak Cation Exchange Separation of Proteins Charge Variants,” presented by Shane Bechler of Thermo Fisher Scientific, at 11:05 am.
Best of the Week: Food Analysis, Chemical Migration in Plastic Bottles, STEM Researcher of the Year
December 20th 2024Top articles published this week include the launch of our “From Lab to Table” content series, a Q&A interview about using liquid chromatography–high-resolution mass spectrometry (LC–HRMS) to assess chemical hazards in plastic bottles, and a piece recognizing Brett Paull for being named Tasmanian STEM Researcher of the Year.
Using LC-MS/MS to Measure Testosterone in Dried Blood Spots
December 19th 2024Testosterone measurements are typically performed using serum or plasma, but this presents several logistical challenges, especially for sample collection, storage, and transport. In a recently published article, Yehudah Gruenstein of the University of Miami explored key insights gained from dried blood spot assay validation for testosterone measurement.
Determination of Pharmaceuticals by Capillary HPLC-MS/MS (Dec 2024)
December 19th 2024This application note demonstrates the use of a compact portable capillary liquid chromatograph, the Axcend Focus LC, coupled to an Agilent Ultivo triple quadrupole mass spectrometer for quantitative analysis of pharmaceutical drugs in model aqueous samples.
