Biotage to Host Programs on Organic Synthesis
Biotage (Uppsala, Sweden) announced plans to sponsor summer programs for chemists to learn about the latest approaches for the rapid production of novel compounds.
Biotage (Uppsala, Sweden) announced plans to sponsor summer programs for chemists to learn about the latest approaches for the rapid production of novel compounds. The three-day programs will be held July 21-23, 2008, at the University of Richmond (Virginia) and July 29-31, 2008, at the University of Edinburgh (UK). According to the company, the programs will bring together industry and academic leaders for discussion of issues such as solid-supported reagents and scavengers in microwave synthesis, microwave-accelerated metal-catalyzed transformations, and flow synthesis. Workshops will focus on streamlining workflows with microwave and flash purification systems, scavengers, reagents, and reaciton work-up products. The programs will also include poster sessions.
LC–MS/MS Quantification of Plasma Proteins in Elephant Seals to Advance Wildlife Conservation
November 12th 2024Liquid chromatography and tandem mass spectrometry (LC–MS/MS) was used to show that repeated stress can cause delayed but sustained changes in blood plasma proteins associated with water conservation, immune responses, fat metabolism, insulin sensitivity, iron recycling, and hormone transport in elephant seals. Some of these changes may be novel markers of recent and chronic stress exposure in marine mammals.
AI and GenAI Applications to Help Optimize Purification and Yield of Antibodies From Plasma
October 31st 2024Deriving antibodies from plasma products involves several steps, typically starting from the collection of plasma and ending with the purification of the desired antibodies. These are: plasma collection; plasma pooling; fractionation; antibody purification; concentration and formulation; quality control; and packaging and storage. This process results in a purified antibody product that can be used for therapeutic purposes, diagnostic tests, or research. Each step is critical to ensure the safety, efficacy, and quality of the final product. Applications of AI/GenAI in many of these steps can significantly help in the optimization of purification and yield of the desired antibodies. Some specific use-cases are: selecting and optimizing plasma units for optimized plasma pooling; GenAI solution for enterprise search on internal knowledge portal; analysing and optimizing production batch profitability, inventory, yields; monitoring production batch key performance indicators for outlier identification; monitoring production equipment to predict maintenance events; and reducing quality control laboratory testing turnaround time.
